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OSBPL11 Knockout Cell Lines

Gene: OSBPL11

Official Full Name: oxysterol binding protein like 11provided by HGNC

Gene Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05665 OSBPL11 Knockout cell line (HeLa) Human OSBPL11 1:3~1:6 Negative Online Inquiry
KO05666 OSBPL11 Knockout cell line (HCT 116) Human OSBPL11 1:2~1:4 Negative Online Inquiry
KO05667 OSBPL11 Knockout cell line (HEK293) Human OSBPL11 1:3~1:6 Negative Online Inquiry
KO05668 OSBPL11 Knockout cell line (A549) Human OSBPL11 1:3~1:4 Negative Online Inquiry

Background

OSBPL11 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to lack the expression of the OSBPL11 gene, a member of the oxysterol-binding protein-like family. These cell lines facilitate the in-depth study of OSBPL11's role in cellular processes, particularly its involvement in lipid metabolism, membrane trafficking, and cellular signaling pathways. By utilizing CRISPR/Cas9 or RNA interference techniques, the OSBPL11 gene is successfully knocked out, allowing researchers to observe the physiological and molecular consequences of its absence.

The functionality of OSBPL11 is particularly noteworthy, as it interacts with various lipids and plays a pivotal role in cellular homeostasis and response to environmental stressors. Knockout models are indispensable for uncovering the mechanistic pathways associated with OSBPL11, which can ultimately contribute to a better understanding of metabolic disorders and their implications in disease states such as obesity and atherosclerosis.

In research and clinical settings, these knockout cell lines serve as powerful tools for screening compounds that target lipid metabolism and designing gene therapy approaches. The ability to manipulate and analyze the effects of OSBPL11 loss offers significant insights into therapeutic interventions for related diseases, thereby providing an invaluable asset for advancing biomedical research.

Compared to alternative approaches such as wild-type cell studies or transient gene silencing, OSBPL11 Gene Knockout Cell Lines provide stable and consistent models that yield reproducible results over time, enabling more accurate and insightful research findings. Researchers can rely on these specialized models to explore gene function with confidence, which is fundamental for experimental rigor.

The value of OSBPL11 Gene Knockout Cell Lines is clear. They not only enhance the understanding of lipid dynamics and associated disorders but also offer a robust platform for therapeutic development. Our company is dedicated to supplying high-quality, genetically distinct cellular models, backed by a team of experts in genetic engineering and cell biology, committed to facilitating groundbreaking research and innovations in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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