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NID1 Knockout Cell Lines

Gene: NID1

Official Full Name: nidogen 1provided by HGNC

Gene Summary: This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36358 NID1 Knockout cell line (HeLa) Human NID1 1:3~1:6 Negative Online Inquiry
KO36359 NID1 Knockout cell line (HEK293) Human NID1 1:3~1:6 Negative Online Inquiry
KO36360 NID1 Knockout cell line (A549) Human NID1 1:3~1:4 Negative Online Inquiry

Background

NID1 Gene Knockout Cell Lines are genetically engineered cell lines that facilitate the study of the Nidogen 1 gene (NID1), which encodes a key extracellular matrix protein integral to the structural framework of tissues. By creating knockout models of this gene, researchers can investigate the gene's role in cellular behaviors such as adhesion, migration, and communication, thus elucidating its contribution to tissue integrity and function.

These cell lines leverage CRISPR-Cas9 gene-editing technology to achieve precise disruption of the NID1 gene, resulting in a versatile platform for functional studies. Scientists can observe phenotypic changes associated with NID1 deficiency and assess implications in different biological contexts, including cancer metastasis, wound healing, and developmental biology. This allows for a deeper understanding of various pathologies linked to extracellular matrix dysregulation.

The scientific importance of NID1 Gene Knockout Cell Lines is underscored by their application in both research and clinical settings. They serve as invaluable tools for drug discovery and testing, particularly in the oncology field, where the interaction between cells and their surrounding matrix is essential to tumor progression and metastasis. Moreover, these knockout models can aid in the development of innovative therapeutic strategies targeting extracellular matrix components.

One of the key advantages of our NID1 Gene Knockout Cell Lines is their high specificity and reproducibility, which surpasses traditional methods of gene knockdown. Compared to competitors, our product offers a more streamlined approach with a robust validation process, ensuring that the phenotypic outcomes are directly attributable to NID1 loss-of-function.

For researchers and clinicians focused on the intricacies of cell biology and disease mechanisms, our NID1 Gene Knockout Cell Lines provide a unique opportunity to dissect complex biological processes with precision. As a leader in biological research tools, our company is committed to providing high-quality, scientifically engineered products that empower advancements in the field, supporting your quest for discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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