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NCK2 Knockout Cell Lines

Gene: NCK2

Official Full Name: NCK adaptor protein 2provided by HGNC

Gene Summary: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34174 NCK2 Knockout cell line (HeLa) Human NCK2 1:3~1:6 Negative Online Inquiry
KO34175 NCK2 Knockout cell line (HCT 116) Human NCK2 1:2~1:4 Negative Online Inquiry
KO34176 NCK2 Knockout cell line (HEK293) Human NCK2 1:3~1:6 Negative Online Inquiry
KO34177 NCK2 Knockout cell line (A549) Human NCK2 1:3~1:4 Negative Online Inquiry

Background

NCK2 Gene Knockout Cell Lines are advanced research tools designed to facilitate the exploration of cellular pathways and mechanisms influenced by the NCK2 gene, a critical component in various signaling pathways involving growth factor receptor dynamics, cytoskeletal organization, and cellular motility. These cell lines are created through precise gene editing technologies, such as CRISPR/Cas9, ensuring a robust and reliable absence of the NCK2 protein, which allows researchers to closely examine the implications of its loss on cellular behavior and physiology.

The primary function of NCK2 Gene Knockout Cell Lines is to serve as a reliable model for studying the role of NCK2 in cell migration, proliferation, and differentiation. By comparing the NCK2-deficient cells to wild-type controls, scientists can investigate alterations in key signaling pathways and understand the broader implications of NCK2 in pathologies such as cancer, cardiovascular diseases, and developmental disorders. This functional analysis is critical for elucidating the molecular mechanisms underpinning a variety of biological processes and for developing targeted therapeutic strategies.

From a scientific perspective, the applications of NCK2 Gene Knockout Cell Lines extend into both basic research and clinical settings. Researchers can utilize these models to identify novel drug targets and to validate hypotheses regarding the contribution of NCK2 to disease progression, making them invaluable in the movement toward personalized medicine.

Compared to traditional methods of gene silencing or overexpression techniques, NCK2 Gene Knockout Cell Lines offer unparalleled specificity and permanence, allowing for long-term studies and more accurate representations of physiological conditions. This specificity significantly reduces experimental variability and increases the reproducibility of results, granting greater confidence in scientific conclusions.

For researchers and clinicians alike, the value of NCK2 Gene Knockout Cell Lines lies in their ability to unlock crucial insights into cellular functions and disease mechanisms. By leveraging this product, users can enhance their research capabilities, promote innovative scientific inquiries, and contribute to the advancement of therapeutic strategies.

Our company specializes in providing high-quality biological products that support advancements in cellular and molecular biology research. With our expertise and commitment to scientific innovation, we ensure that our NCK2 Gene Knockout Cell Lines meet the rigorous demands of researchers and clinicians, facilitating groundbreaking discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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