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MXD1 Knockout Cell Lines

Gene: MXD1

Official Full Name: MAX dimerization protein 1provided by HGNC

Gene Summary: This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36740 MXD1 Knockout cell line (HeLa) Human MXD1 1:3~1:6 Negative Online Inquiry
KO36741 MXD1 Knockout cell line (HCT 116) Human MXD1 1:2~1:4 Negative Online Inquiry
KO36742 MXD1 Knockout cell line (HEK293) Human MXD1 1:3~1:6 Negative Online Inquiry
KO36743 MXD1 Knockout cell line (A549) Human MXD1 1:3~1:4 Negative Online Inquiry

Background

MXD1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to exhibit a complete loss of the MXD1 gene, a crucial regulator in various cellular processes, including proliferation, differentiation, and apoptosis. This product serves as a pivotal tool for studying the gene’s role in cellular pathways and its implications in oncogenesis, metabolic disorders, and neurodegenerative diseases.

The primary mechanism of action lies in the knockout of the MXD1 gene, which facilitates the investigation of downstream signaling pathways, specifically those influenced by transcription factors that regulate gene expression in response to physiological stimuli. By employing these knockout cell lines, researchers can elucidate the gene's function and its contributions to disease pathology, exploring the impact of its absence on cell behavior in both in vitro and in vivo systems.

The scientific significance of MXD1 Gene Knockout Cell Lines is underscored by their wide-ranging applications in biomedical research, including drug discovery, cancer biology, and the study of metabolic syndrome. This product allows for the investigation of therapeutic targets and the identification of biomarkers critical for advancing personalized medicine approaches.

One of the unique selling points of MXD1 Gene Knockout Cell Lines is their ability to provide highly reproducible and reliable results compared to traditional methods, such as pharmacological inhibition or transient transfection. Furthermore, these cell lines enable researchers to conduct long-term studies and observe cumulative effects, an advantage that is often not feasible with transient approaches.

For researchers and clinicians, the value of utilizing MXD1 Gene Knockout Cell Lines cannot be overstated. These engineered lines not only enhance experimental rigor and reproducibility but also provide insights that could lead to novel therapeutic strategies. By bridging the gap between basic research and clinical application, MXD1 Gene Knockout Cell Lines position themselves as an essential tool in today's rapidly evolving landscape of genetic research.

Our company is dedicated to advancing biological research through high-quality products and innovative solutions. With our expertise in genomic technologies, we pride ourselves on offering well-characterized cell lines and comprehensive support, empowering scientists to push the boundaries of knowledge in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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