Gene: MTMR6
Official Full Name: myotubularin related protein 6provided by HGNC
Gene Summary: Enables phosphatidylinositol-3,5-bisphosphate phosphatase activity and phosphatidylinositol-3-phosphate phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Located in cytoplasm and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07863 | MTMR6 Knockout cell line (HeLa) | Human | MTMR6 | 1:3~1:6 | Negative | Online Inquiry |
KO07864 | MTMR6 Knockout cell line (HCT 116) | Human | MTMR6 | 1:2~1:4 | Negative | Online Inquiry |
KO07865 | MTMR6 Knockout cell line (HEK293) | Human | MTMR6 | 1:3~1:6 | Negative | Online Inquiry |
KO07866 | MTMR6 Knockout cell line (A549) | Human | MTMR6 | 1:3~1:4 | Negative | Online Inquiry |
MTMR6 Gene Knockout Cell Lines are innovative biological tools created by deliberately disrupting the MTMR6 gene, which encodes for the myotubularin-related protein 6. This knockout model is designed to facilitate detailed investigation into the physiological roles of the MTMR6 gene and its associated pathways. The gene itself is implicated in various cellular processes, including autophagy, lipid metabolism, and cellular signaling. By utilizing these knockout cell lines, researchers can delve into the underlying mechanisms by which MTMR6 influences these critical processes.
The primary function of the MTMR6 Gene Knockout Cell Lines is to provide a stable and reproducible system for studying the effects of the absence of MTMR6. The cell lines exhibit altered lipid profiles and changes in autophagic activity, permitting scientists to explore the gene’s role in disease models, particularly in neuromuscular disorders where MTMR6 plays a significant part in muscle cell maintenance and integrity. This product opens avenues for understanding pathologies linked to MTMR6 dysfunction, such as Charcot-Marie-Tooth disease.
The scientific importance of these knockout cell lines extends to both basic research and clinical applications. Investigators can utilize these models to test therapeutic strategies targeting pathways affected by MTMR6, and to screen potential drug candidates that may mitigate the adverse effects of MTMR6 loss. Additionally, the MTMR6 knockout model may serve to provide insights into the molecular biology of related conditions, establishing a foundation for the development of targeted treatments.
Compared to alternatives, which often rely on non-specific methods of gene silencing, MTMR6 Gene Knockout Cell Lines provide a precise, heritable alteration that ensures consistent experimental outcomes. The specificity of this knockout approach reduces background variability that can confound data interpretation, making it easier for researchers to draw meaningful conclusions regarding the functional role of MTMR6 in various contexts.
For researchers and clinicians seeking to advance their understanding of MTMR6 and its implications in disease, this product offers a robust tool that enhances experimental reliability and facilitates high-impact discoveries. With extensive experience in developing cellular models and a commitment to innovation, our company stands at the forefront of biological research, providing high-quality products that empower the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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