Gene: MLF1
Official Full Name: myeloid leukemia factor 1provided by HGNC
Gene Summary: This gene encodes an oncoprotein which is thought to play a role in the phenotypic determination of hemopoetic cells. Translocations between this gene and nucleophosmin have been associated with myelodysplastic syndrome and acute myeloid leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02972 | MLF1 Knockout cell line (HeLa) | Human | MLF1 | 1:3~1:6 | Negative | Online Inquiry |
KO02973 | MLF1 Knockout cell line (HCT 116) | Human | MLF1 | 1:2~1:4 | Negative | Online Inquiry |
KO02974 | MLF1 Knockout cell line (HEK293) | Human | MLF1 | 1:3~1:6 | Negative | Online Inquiry |
KO02975 | MLF1 Knockout cell line (A549) | Human | MLF1 | 1:3~1:4 | Negative | Online Inquiry |
MLF1 Gene Knockout Cell Lines are genetically modified cells specifically engineered to lack the expression of the MLF1 (Myeloid Leukemia Factor 1) gene. This product serves as a vital tool in the study of myeloid malignancies, cancer biology, and cellular signaling pathways. These knockout cell lines allow researchers to dissect the functional consequences of MLF1 deficiency, thereby elucidating its role in hematopoiesis and tumorigenesis.
The primary function of the MLF1 gene within normal cellular processes includes regulating gene expression and mediating signal transduction pathways that influence cell growth and differentiation. Through techniques such as CRISPR-Cas9 gene editing, our MLF1 knockout cell lines enable scientists to investigate the specific biological mechanisms and molecular interactions that occur when MLF1 is absent. This research can unveil potential therapeutic targets for myeloid leukemias and related disorders.
Scientifically, the MLF1 gene knockout cell lines represent a crucial advancement in understanding the etiology of hematological cancers. They can be utilized in various research paradigms, from drug screening to gene therapy development, fostering innovation in precision medicine. In clinical settings, insights derived from these studies could direct future treatment strategies and improve patient outcomes.
What sets our MLF1 Gene Knockout Cell Lines apart from alternatives on the market is the high specificity and efficiency of our gene-editing techniques, along with the robust characterization of these cell lines. Each line comes with extensive phenotype validation data, ensuring that researchers can trust the results obtained during experiments.
For researchers and clinicians focused on cancer biology and therapeutic development, the MLF1 Gene Knockout Cell Lines represent an invaluable resource for advancing knowledge and treatment options. Our company, with its commitment to high-quality biological products and extensive experience in genetic engineering, delivers cutting-edge tools to empower your research and clinical initiatives. We are dedicated to contributing to the scientific community with reliable, innovative solutions that facilitate groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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