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MAP1B Knockout Cell Lines

Gene: MAP1B

Official Full Name: microtubule associated protein 1Bprovided by HGNC

Gene Summary: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36716 MAP1B Knockout cell line (HeLa) Human MAP1B 1:3~1:6 Negative Online Inquiry
KO36717 MAP1B Knockout cell line (HCT 116) Human MAP1B 1:2~1:4 Negative Online Inquiry
KO36718 MAP1B Knockout cell line (HEK293) Human MAP1B 1:3~1:6 Negative Online Inquiry
KO36719 MAP1B Knockout cell line (A549) Human MAP1B 1:3~1:4 Negative Online Inquiry

Background

MAP1B Gene Knockout Cell Lines are a cutting-edge biological product designed for advanced research into the roles of the MAP1B gene, which encodes a crucial protein involved in neurodevelopment and synaptic function. These cell lines have been developed using CRISPR-Cas9 gene-editing technology, rendering them indispensable tools for studying the molecular mechanisms of neurological diseases and cell signaling pathways.

The key functionality of MAP1B Gene Knockout Cell Lines lies in their precise deletion of the MAP1B gene, allowing researchers to assess the gene's role in neuronal differentiation, axonogenesis, and synaptic plasticity. By observing cellular responses in the absence of MAP1B, scientists can unravel its contribution to conditions such as neurodegenerative diseases, autism spectrum disorders, and traumatic brain injuries. The knockout model is further complemented by various assays that characterize alterations in cellular morphology, signaling cascades, and gene expression profiles.

Scientifically, the MAP1B knockout model holds tremendous importance in both fundamental and applied research settings. In the lab, it provides a platform for drug discovery, therapeutic interventions, and studies regarding gene-environment interactions. Clinically, understanding MAP1B's function may lead to identifying novel biomarkers for neurological disorders, paving the way for personalized medicine approaches.

Compared to traditional wild-type models or even other knockout cell lines, MAP1B Gene Knockout Cell Lines offer distinct advantages. Their use increases reproducibility and specificity of results, drastically reducing background noise typically associated with non-targeted approaches. Moreover, these cell lines are rigorously validated, ensuring they meet the highest quality standards that researchers expect.

The value proposition for researchers and clinicians is clear: MAP1B Gene Knockout Cell Lines empower the scientific community to dissect complex neurobiological processes with unparalleled precision. By utilizing these innovative tools, users can move towards breakthroughs that may transform our understanding and treatment of neurological conditions.

Our company specializes in providing high-quality biological products tailored for genetic and molecular studies, backed by years of expertise in cellular engineering and a commitment to advancing research. We are dedicated to supporting your scientific journey with precise, reliable solutions that drive discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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