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MAMLD1 Knockout Cell Lines

Gene: MAMLD1

Official Full Name: mastermind like domain containing 1provided by HGNC

Gene Summary: This gene encodes a mastermind-like domain containing protein. This protein may function as a transcriptional co-activator. Mutations in this gene are the cause of X-linked hypospadias type 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16365 MAMLD1 Knockout cell line (HeLa) Human MAMLD1 1:3~1:6 Negative Online Inquiry
KO16366 MAMLD1 Knockout cell line (HCT 116) Human MAMLD1 1:2~1:4 Negative Online Inquiry
KO16367 MAMLD1 Knockout cell line (A549) Human MAMLD1 1:3~1:4 Negative Online Inquiry

Background

MAMLD1 Gene Knockout Cell Lines are specialized cellular models designed to study the functional role of the MAMLD1 gene, a critical player in various biological processes related to gene expression, cellular differentiation, and signaling pathways. These cell lines have been meticulously engineered to lack the MAMLD1 gene, allowing researchers to investigate the consequences of its absence on cellular behavior and phenotypic outcomes.

The primary function of MAMLD1 (Mastermind-like Domain Containing 1) is tied to the regulation of Notch signaling, a pathway pivotal for cellular communication and developmental processes. By utilizing MAMLD1 Gene Knockout Cell Lines, scientists can explore how the absence of this gene affects cell proliferation, apoptosis, and differentiation, providing insights into its involvement in diseases such as cancer and congenital disorders.

The scientific importance of these cell lines cannot be overstated, as they serve as valuable tools in both fundamental research and clinical applications. In particular, they offer a unique opportunity to model specific pathologies, screen for therapeutic targets, and validate drug candidates in a setting that mimics disease conditions without the ethical and logistical constraints of working with human subjects.

Compared to traditional wild-type cell lines, MAMLD1 Gene Knockout Cell Lines exemplify a significant advancement by providing a more precise framework for understanding gene function and pathway interactions. They are rigorously validated and characterized to ensure reproducibility, thereby enhancing the reliability of experimental results.

Researchers and clinicians will find these knockouts invaluable for dissecting the molecular mechanisms underlying MAMLD1-related conditions, facilitating the development of novel therapeutic strategies. With a keen focus on precision medicine, these cell lines represent a powerful resource for generating more effective treatments.

Our company prides itself on its cutting-edge innovations in cell line development and molecular genetics, ensuring that our products meet the highest standards of quality and relevance for contemporary biological research. By providing MAMLD1 Gene Knockout Cell Lines, we are committed to empowering researchers with the tools they need to advance their work and foster significant discoveries in the realm of genomics and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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