Gene: MACROD2
Official Full Name: mono-ADP ribosylhydrolase 2provided by HGNC
Gene Summary: The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25555 | MACROD2 Knockout cell line (HeLa) | Human | MACROD2 | 1:3~1:6 | Negative | Online Inquiry |
KO25556 | MACROD2 Knockout cell line (HCT 116) | Human | MACROD2 | 1:2~1:4 | Negative | Online Inquiry |
KO25557 | MACROD2 Knockout cell line (HEK293) | Human | MACROD2 | 1:3~1:6 | Negative | Online Inquiry |
MACROD2 Gene Knockout Cell Lines are specialized models designed to facilitate in-depth research into the functions and regulatory mechanisms of the MACROD2 gene, which is integral to cellular processes such as DNA repair, response to oxidative stress, and metabolic regulation. These knockout cell lines are engineered using advanced CRISPR-Cas9 gene-editing technology, ensuring precise disruption of the MACROD2 gene, allowing researchers to investigate the resulting phenotypic changes and cellular behaviors that emerge in its absence.
The key function of MACROD2 is linked to its involvement in mono-ADP-ribosylation, a post-translational modification that impacts protein interactions and signaling pathways. By creating a model where this gene is knocked out, investigators can examine the downstream effects on cellular mechanisms such as apoptosis, proliferation, and metabolic pathways. This unique capability of observing the direct consequences of MACROD2 loss enables researchers to elucidate its role in disease contexts, including cancer and neurodegenerative disorders.
The scientific importance of MACROD2 Gene Knockout Cell Lines lies in their application across various research fields, including molecular biology, pharmacology, and genetics. These cell lines serve as a powerful tool for drug discovery, biomarker identification, and the validation of new therapeutic approaches, especially in understanding complex diseases where MACROD2 is implicated.
Compared to conventional methods that rely on pharmacological inhibition or transient transfection, MACROD2 Gene Knockout Cell Lines offer a more stable and reproducible system for targeted studies, drastically improving experimental reliability. Additionally, these knockout models are compatible with high-throughput screening, making them suitable for large-scale applications in research settings.
For researchers and clinicians focused on gene function and disease mechanisms, utilizing MACROD2 Gene Knockout Cell Lines is a strategic investment. Their ability to unveil novel insights and contribute to the development of innovative therapies presents a significant advantage in a rapidly evolving scientific landscape.
Our company specializes in providing high-quality biological products and is committed to advancing scientific discovery with rigorously validated models like MACROD2 Gene Knockout Cell Lines, ensuring that our partners in research are empowered with the best tools available to tackle today’s complex biological questions.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.