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LRP4 Knockout Cell Lines

Gene: LRP4

Official Full Name: LDL receptor related protein 4provided by HGNC

Gene Summary: This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05393 LRP4 Knockout cell line (HeLa) Human LRP4 1:3~1:6 Negative Online Inquiry
KO05394 LRP4 Knockout cell line (HCT 116) Human LRP4 1:2~1:4 Negative Online Inquiry
KO05395 LRP4 Knockout cell line (HEK293) Human LRP4 1:3~1:6 Negative Online Inquiry
KO05396 LRP4 Knockout cell line (A549) Human LRP4 1:3~1:4 Negative Online Inquiry

Background

LRP4 Gene Knockout Cell Lines are specialized biological tools developed through targeted gene editing techniques, specifically designed to investigate the role and functionality of the LDL receptor-related protein 4 (LRP4) in various biological processes. These cell lines possess a disrupted LRP4 gene, enabling researchers to study the implications of LRP4 deficiency in cellular signaling pathways, receptor interactions, and overall cellular behavior.

The primary function of LRP4 is to mediate critical cellular processes, including neuronal development, synaptic health, and muscle function, by acting as a receptor for various ligands. These knockout cell lines allow scientists to elucidate how the absence of LRP4 affects signaling cascades, thereby providing insights into disease mechanisms associated with neuromuscular disorders and cognitive impairments. By utilizing CRISPR technology or other gene-editing methodologies to create these knockout models, researchers can explore phenotype alterations, gene expression changes, and downstream signaling pathways associated with LRP4.

The scientific importance of LRP4 Gene Knockout Cell Lines extends across research disciplines, particularly in understanding genetic diseases, pharmacological response assessments, and tissue regeneration studies. Their application in both basic research and clinical settings offers a platform for drug discovery and development, especially for therapeutics targeting LRP4-related pathways.

A key advantage of our LRP4 Gene Knockout Cell Lines is the specificity and efficiency with which the LRP4 gene has been edited, which minimizes off-target effects often associated with gene-editing technologies. Additionally, these knockout lines are generated with stringent quality control measures, ensuring consistent performance across different labs and experiments.

For researchers, clinicians, and pharmaceutical companies, these cell lines enhance the ability to model diseases, explore novel therapeutic targets, and advance understanding in a field where traditional models may fall short. By choosing our LRP4 Gene Knockout Cell Lines, users gain access to a high-quality, reliable resource that propels their research forward in a rapidly evolving scientific landscape.

Our company specializes in providing innovative biological solutions tailored to the needs of the research community, leveraging extensive experience in gene editing and cell line development to support cutting-edge investigations in molecular biology and translational medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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