Gene: LPAR3
Official Full Name: lysophosphatidic acid receptor 3provided by HGNC
Gene Summary: This gene encodes a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10231 | LPAR3 Knockout cell line (HCT 116) | Human | LPAR3 | 1:2~1:4 | Negative | Online Inquiry |
KO10232 | LPAR3 Knockout cell line (HEK293) | Human | LPAR3 | 1:3~1:6 | Negative | Online Inquiry |
LPAR3 Gene Knockout Cell Lines represent a groundbreaking advancement in cellular biology, designed for researchers aiming to study the specific functions and pathways regulated by the Lysophosphatidic Acid Receptor 3 (LPAR3). These cell lines are genetically engineered to express a complete knockout of the LPAR3 gene, thereby enabling the precise analysis of downstream signaling mechanisms and physiological responses associated with LPA signaling. The cell lines provide a controlled environment for investigating the role of LPAR3 in cellular processes such as motility, proliferation, and differentiation.
The key function of LPAR3 involves its interaction with lysophosphatidic acid, a bioactive lipid known to influence various cellular activities through G-protein-coupled receptor signaling. By employing these knockout cell lines, researchers can elucidate the receptor's contributions in pathological conditions, including cancer metastasis and fibrotic diseases, where LPAR3 is hypothesized to play a prominent role.
The scientific importance of these cell lines extends to their applications in drug discovery and development, where they serve as valuable tools for screening potential therapeutic agents that can selectively modulate LPAR3 signaling. In clinical settings, these cell lines are pivotal for understanding the molecular basis of LPAR3-associated diseases and fostering the development of novel targeted therapies.
What sets our LPAR3 Gene Knockout Cell Lines apart from alternatives is their high specificity, validated performance, and the comprehensive characterization data supporting their use. Unlike transient knockdowns that may not provide consistent results, these stable knockout lines allow for reproducible experimental outcomes, facilitating long-term studies and real-time analysis.
For researchers and clinicians dedicated to the fields of pharmacology, oncology, and cell biology, our LPAR3 Gene Knockout Cell Lines offer an unparalleled resource to advance their understanding of LPAR3-driven mechanisms. With a strong foundation in bioresearch and a commitment to delivering cutting-edge biological products, our company exemplifies expertise in providing scientists with the tools necessary for impactful discoveries in the realm of cellular and molecular science.
Please note that all services are for research use only. Not intended for any clinical use.
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