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LCOR Knockout Cell Lines

Gene: LCOR

Official Full Name: ligand dependent nuclear receptor corepressorprovided by HGNC

Gene Summary: LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24857 LCOR Knockout cell line (HeLa) Human LCOR 1:3~1:6 Negative Online Inquiry
KO24858 LCOR Knockout cell line (HCT 116) Human LCOR 1:2~1:4 Negative Online Inquiry
KO24859 LCOR Knockout cell line (HEK293) Human LCOR 1:3~1:6 Negative Online Inquiry
KO24860 LCOR Knockout cell line (A549) Human LCOR 1:3~1:4 Negative Online Inquiry

Background

LCOR Gene Knockout Cell Lines are engineered cellular models designed to selectively inactivate the LCOR gene, which is implicated in various biological processes, including gene regulation and metabolic pathways. These cell lines are generated through advanced CRISPR-Cas9 technology, allowing for precise modifications in the genome that facilitate the study of gene function, signaling pathways, and disease mechanisms.

The primary function of the LCOR Gene Knockout Cell Lines lies in their unique utility as tools for elucidating the role of the LCOR gene in health and disease contexts. By disrupting the normal expression of this gene, researchers can investigate the resulting phenotypic changes, enabling detailed studies on cellular responses, differentiation, and dysregulation that may contribute to conditions such as cancer and metabolic syndromes. Furthermore, these cell lines can be integral in pharmacological screening and the development of novel therapeutics targeting LCOR-related pathways.

Scientifically, the introduction of LCOR Gene Knockout Cell Lines into research labs offers significant advancements by providing a platform for high-throughput screening and functional assays that were previously limited by the availability of suitable models. They serve as crucial components in validating gene-targeted therapies and exploring the intricate networks of gene interactions.

What sets our LCOR Gene Knockout Cell Lines apart from competitors is their high specificity, reliability, and ease of use. Unlike other traditional knockout models that may exhibit off-target effects or require extensive breeding, our cell lines are optimized to deliver consistent performance with minimal variability. They align seamlessly with common laboratory protocols, thus reducing the time and resources typically associated with developing novel cell models.

For researchers and clinicians, these cell lines provide invaluable insights into the gene's biological roles, accelerating the translation of laboratory findings into clinical applications. Their accessibility and targeted approach enhance experimental reproducibility, making them an essential tool in biomedical research.

At [Your Company Name], we are committed to supporting the scientific community with high-quality biological products. Our expertise in genetic engineering and cell line development ensures that our offerings, including the LCOR Gene Knockout Cell Lines, meet the rigorous standards required for cutting-edge research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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