Gene: JKAMP
Official Full Name: JNK1/MAPK8 associated membrane proteinprovided by HGNC
Gene Summary: Enables ubiquitin protein ligase binding activity. Involved in ERAD pathway. Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04780 | JKAMP Knockout cell line (HeLa) | Human | JKAMP | 1:3~1:6 | Negative | Online Inquiry |
KO04781 | JKAMP Knockout cell line (HCT 116) | Human | JKAMP | 1:2~1:4 | Negative | Online Inquiry |
KO04782 | JKAMP Knockout cell line (HEK293) | Human | JKAMP | 1:3~1:6 | Negative | Online Inquiry |
KO04783 | JKAMP Knockout cell line (A549) | Human | JKAMP | 1:3~1:4 | Negative | Online Inquiry |
JKAMP Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of gene function, disease mechanisms, and therapeutic interventions by enabling specific gene knockouts. These cell lines utilize targeted gene editing technologies, such as CRISPR-Cas9, to create precise deletions of specific genes, thereby allowing researchers to observe the resultant phenotypic changes and biochemical pathways involved.
The primary function of JKAMP Gene Knockout Cell Lines lies in their ability to mimic the loss-of-function mutations observed in various diseases. By disrupting particular genes, researchers can investigate how these alterations affect cellular behavior, signaling pathways, and response to drugs. This mechanistic insight is crucial for understanding complex diseases, including cancer, neurodegeneration, and metabolic disorders, ultimately leading to the development of targeted therapies and novel treatments.
In both research and clinical settings, these cell lines hold immense value. Their applications range from basic biological research to drug discovery, biomarker identification, and preclinical testing. Additionally, the availability of specific knockout lines allows for high-throughput screening of small molecules or genetic modifiers, accelerating the pace of scientific discovery while reducing reliance on animal models.
Compared to traditional methods of gene knockout, such as random mutagenesis or RNA interference, JKAMP Gene Knockout Cell Lines offer unparalleled specificity and efficiency. Researchers benefit from the reproducibility and consistency of cell lines derived from the same genetic background, which enhances the reliability of experimental results. Furthermore, the user-friendly nature of these products, paired with comprehensive supporting documentation, empowers researchers to streamline their workflows effectively.
Ultimately, JKAMP Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology. They provide essential tools for unlocking the complexities of gene function and elucidating the underlying mechanisms of diseases. Backed by our company’s robust expertise in genetic engineering and cellular models, we are committed to supplying researchers and clinicians with innovative biological products that enhance the quality of their work and support groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.