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IRX4 Knockout Cell Lines

Gene: IRX4

Official Full Name: iroquois homeobox 4provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within heart development. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23305 IRX4 Knockout cell line (HCT 116) Human IRX4 1:2~1:4 Negative Online Inquiry

Background

IRX4 Gene Knockout Cell Lines represent a significant advancement in cellular biology research, designed to facilitate the exploration of gene function and regulation. These specialized cell lines are engineered to lack the IRX4 gene, a crucial player in embryonic development and various physiological processes. By removing the IRX4 gene, researchers gain a powerful tool to investigate the downstream effects on cellular pathways, gene expression profiles, and phenotypic outcomes.

The primary function of the IRX4 Gene Knockout Cell Lines lies in their ability to provide insights into the regulatory networks governed by the IRX4 gene. This is achieved through mechanisms such as gene expression analysis, where the absence of IRX4 allows for comparison with wild-type cells, elucidating its role in developmental processes and disease mechanisms. This knockout model is particularly valuable in studies related to cardiac development, as IRX4 is implicated in heart morphogenesis and function.

The scientific importance of these cell lines extends across various research applications, from basic biology to translational studies. In clinical settings, they serve as powerful models for investigating genetic disorders and potential therapeutic interventions. By understanding the consequences of IRX4 knockout, researchers can identify novel targets for drug development and better understand the pathology of diseases linked to IRX4 dysregulation.

One of the standout advantages of our IRX4 Gene Knockout Cell Lines is their high specificity and reproducibility, ensuring that results are reliable and translatable. Compared to conventional methods such as CRISPR editing, these pre-developed cell lines save valuable time and resources, allowing researchers to focus on their scientific inquiries without the added complexity of creating knockout models from scratch. Furthermore, our cell lines are derived from well-characterized backgrounds, enhancing their utility across diverse experimental setups.

For researchers and clinicians aiming to decode complex genetic interactions and advance their understanding of IRX4-related pathways, these knockout cell lines are an invaluable resource. They provide a robust platform for experimentation and hypothesis testing, driving innovation in genetic research and therapeutic discovery.

Our company specializes in the development of high-quality biological products that empower researchers in their quest for answers in genetics and cellular biology. With our expertise and commitment to excellence, we are dedicated to supporting scientific advancements through our carefully crafted product offerings.

Please note that all services are for research use only. Not intended for any clinical use.

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