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GPR157 Knockout Cell Lines

Gene: GPR157

Official Full Name: G protein-coupled receptor 157provided by HGNC

Gene Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; phospholipase C-activating G protein-coupled receptor signaling pathway; and radial glial cell differentiation. Predicted to be located in ciliary membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26258 GPR157 Knockout cell line (HeLa) Human GPR157 1:3~1:6 Negative Online Inquiry
KO26259 GPR157 Knockout cell line (HCT 116) Human GPR157 1:2~1:4 Negative Online Inquiry
KO26260 GPR157 Knockout cell line (HEK293) Human GPR157 1:3~1:6 Negative Online Inquiry
KO26261 GPR157 Knockout cell line (A549) Human GPR157 1:3~1:4 Negative Online Inquiry

Background

GPR157 Gene Knockout Cell Lines are invaluable research tools created through the targeted gene disruption of the GPR157 receptor, a G-protein coupled receptor (GPCR) implicated in various physiological processes, including neurodevelopment and metabolic regulation. These cell lines facilitate the comprehensive study of GPR157's function and its contributions to cellular signaling pathways, offering researchers a distinct opportunity to explore the receptor's role in diseases such as obesity, anxiety, and neurodegenerative disorders.

The primary function of GPR157 involves mediating complex intracellular signaling cascades upon ligand binding, which may influence various downstream effects, including neuronal development and hormone secretion. By utilizing these gene knockout cell lines, researchers can dissect the mechanisms by which GPR157 operates, providing insights into receptor-mediated signaling pathways that could lead to therapeutic advancements.

The scientific importance of GPR157 Gene Knockout Cell Lines extends to both research and clinical settings, as they enable the investigation of GPCR-related drug targets and interactions within various biological contexts. As GPCRs are pivotal in medication development, understanding the specific roles of GPR157 can aid in identifying new drug candidates or therapeutic approaches.

Compared to alternative models, GPR157 Gene Knockout Cell Lines offer specificity and reliability in studying the gene's functions without the confounding effects of other signaling pathways. This targeted knockout approach ensures clarity in experimental findings, thereby affirming its utility in both basic and applied research environments.

Value for researchers and clinicians is underpinned by the potential for significant breakthroughs in understanding the etiology of conditions linked to GPR157, impacting therapeutic interventions and drug discovery.

With expertise in developing high-quality biological products, our company is committed to producing reliable and scientifically robust cell line systems that advance research and improve clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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