Gene: GPC5
Official Full Name: glypican 5provided by HGNC
Gene Summary: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37891 | GPC5 Knockout cell line (HeLa) | Human | GPC5 | 1:3~1:6 | Negative | Online Inquiry |
GPC5 Gene Knockout Cell Lines are genetically modified cell lines specifically altered to disrupt the expression of the glypican-5 (GPC5) gene, which encodes a heparan sulfate proteoglycan involved in cell signaling and growth regulation. These cell lines serve as a powerful tool for researchers investigating the role of GPC5 in various biological processes, including cancer progression and developmental disorders. By knocking out the GPC5 gene, these cell lines allow for the assessment of the gene's function and its interaction with other signaling pathways, offering insights into potential therapeutic targets.
The mechanism of action involves CRISPR-Cas9 technology or other gene-editing techniques, ensuring precision in eliminating the GPC5 gene's expression. As a result, researchers can study the downstream effects of GPC5 loss, such as changes in cell proliferation, migration, and differentiation. The KO cell lines can be utilized in a range of experimental setups, from in vitro assays to in vivo models, making them suitable for diverse research trajectories.
The scientific importance of GPC5 Gene Knockout Cell Lines is underscored by their applications in cancer research, particularly in solid tumors where GPC5 is implicated in tumor growth and metastasis. Furthermore, these cell lines offer insights into therapeutic strategies aimed at manipulating GPC5 pathways, presenting valuable data for drug development and regenerative medicine.
What sets our GPC5 Gene Knockout Cell Lines apart from alternatives is their high efficiency, reproducibility, and comprehensive characterization, which ensure reliability in downstream experiments. Unlike lesser-known cell lines, these knockout models come with validated backgrounds that save time and resources, making them particularly appealing to researchers striving for precise and impactful results.
For researchers and clinicians looking to deepen their understanding of GPC5-related pathways or to develop targeted therapies, our GPC5 Gene Knockout Cell Lines provide an indispensable asset. Backed by our commitment to innovation and quality, our expertise in genetic modifications ensures that you receive top-tier products that contribute meaningfully to your scientific endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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