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FAT3 Knockout Cell Lines

Gene: FAT3

Official Full Name: FAT atypical cadherin 3provided by HGNC

Gene Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within generation of neurons; negative regulation of dendrite development; and retina layer formation. Predicted to be located in dendrite and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30349 FAT3 Knockout cell line (HEK293) Human FAT3 1:3~1:6 Negative Online Inquiry
KO30350 FAT3 Knockout cell line (A549) Human FAT3 1:3~1:4 Negative Online Inquiry

Background

FAT3 Gene Knockout Cell Lines represent a critical advancement in genetic research, specifically designed to facilitate the study of the FAT3 gene's role in cellular processes. These cell lines are created through precise gene editing techniques, successfully disrupting the expression of the FAT3 gene, allowing researchers to investigate the gene's function and its implications in various biological contexts.

The mechanism of action for these knockout cell lines relies on the principles of CRISPR/Cas9 genome editing, which introduces targeted mutations that effectively silence the FAT3 gene. By inhibiting this gene, researchers can study downstream effects on cellular signaling pathways, differentiation, and tissue development. FAT3 has been implicated in both cancer pathways and neurodevelopmental disorders, making these cell lines invaluable for exploring these critical conditions.

The scientific importance of FAT3 Gene Knockout Cell Lines cannot be overstated. They serve as a fundamental tool in understanding gene function, elucidating pathogenic mechanisms, and developing novel therapeutic strategies. In clinical settings, these cell lines can assist in drug discovery and the validation of targeted therapies, providing insights into how interventions may counteract FAT3-related dysfunctions.

Compared to alternative approaches, such as transient knockdown methods or wild-type cell lines, FAT3 Gene Knockout Cell Lines offer sustained disruption of the gene, leading to more reliable and reproducible experimental outcomes. This long-term silencing minimizes compensatory changes often seen in transient systems, thus improving the relevance of experimental findings.

For researchers and clinicians focused on advancing the field of genetics and disease, these knockout cell lines present a unique opportunity to gain deeper insights into gene function and therapeutic development. Backed by our company’s extensive expertise in genetic engineering and a commitment to providing high-quality biological products, FAT3 Gene Knockout Cell Lines are positioned as an essential resource in the quest for scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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