Gene: FAM53A
Official Full Name: family with sequence similarity 53 member Aprovided by HGNC
Gene Summary: Predicted to be involved in protein import into nucleus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21552 | FAM53A Knockout cell line (HEK293) | Human | FAM53A | 1:3~1:6 | Negative | Online Inquiry |
FAM53A Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to ablate the expression of the FAM53A gene, a critical component involved in cellular processes such as cell growth, proliferation, and signaling. These knockout models serve as powerful tools to study the underlying mechanisms of various biological phenomena, including cancer progression and response to therapies. The key functionality of these cell lines lies in their ability to provide researchers with a clear understanding of the gene's role by allowing the examination of phenotypic changes resulting from the absence of FAM53A.
The mechanisms that govern these knockout models often involve the use of CRISPR-Cas9 technology, which ensures precise, site-specific editing of the genome. Researchers can observe variations in cellular behavior, enabling them to delineate the FAM53A gene's involvement in critical pathways, such as those governing cellular stress responses or metabolic regulation.
In scientific and clinical research settings, FAM53A Gene Knockout Cell Lines are invaluable for dissecting the gene’s implications in disease states and therapeutic responses, particularly in cancer biology. Unlike conventional cell lines, these knockout lines allow for more accurate modeling of conditions that may lead to new therapeutic avenues or biomarkers for treatment efficacy.
The unique offering of FAM53A Gene Knockout Cell Lines lies in their robust and reproducible genetic modifications, accompanied by high specificity due to the CRISPR-Cas9 approach. This results in a more reliable analysis, significantly enhancing the quality of experimental results compared to traditional methods such as transient knockdown using siRNA.
For researchers and clinicians striving to unravel the complexities of gene function in health and disease, our FAM53A Gene Knockout Cell Lines represent a cutting-edge resource. With a strong background in genetic engineering and cellular biology, our company is committed to providing high-quality biological products that empower scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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