Gene: FAM149B1
Official Full Name: family with sequence similarity 149 member B1provided by HGNC
Gene Summary: Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27413 | FAM149B1 Knockout cell line (HeLa) | Human | FAM149B1 | 1:3~1:6 | Negative | Online Inquiry |
KO27414 | FAM149B1 Knockout cell line (HCT 116) | Human | FAM149B1 | 1:2~1:4 | Negative | Online Inquiry |
KO27415 | FAM149B1 Knockout cell line (HEK293) | Human | FAM149B1 | 1:3~1:6 | Negative | Online Inquiry |
KO27416 | FAM149B1 Knockout cell line (A549) | Human | FAM149B1 | 1:3~1:4 | Negative | Online Inquiry |
FAM149B1 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional consequences of the FAM149B1 gene deficiency. This gene, located on human chromosome 14, encodes a protein that is believed to play a role in cellular regulation and signaling pathways. The knockout cell lines are generated using advanced CRISPR-Cas9 genome-editing technology, which allows for precise and efficient gene disruption, rendering the FAM149B1 gene non-functional.
The primary function of these cell lines is to facilitate the investigation of the biological role of FAM149B1 in various cellular processes, including proliferation, apoptosis, and stress responses. Researchers can utilize these models to dissect the cellular mechanisms underlying diseases where FAM149B1 is implicated, such as cancers and neurodegenerative disorders. By comparing knockout cells to wild-type counterparts, scientists can gain insights into how the absence of this gene affects cellular behavior and contributes to disease pathology.
From a scientific perspective, FAM149B1 Gene Knockout Cell Lines represent an invaluable tool in both research and clinical settings. They allow for high-throughput screening of potential therapeutics and the elucidation of pathway interactions, which are crucial for developing targeted treatments. Unlike conventional knockdown methods that can yield variable results, our knockout cell lines provide a stable genetic modification, ensuring reproducibility and reliability in experimental outcomes.
One of the distinctive advantages of FAM149B1 Gene Knockout Cell Lines is their versatility; they are suitable for a broad range of applications, from basic research to the testing of drug candidates. Moreover, our product is supplied with comprehensive support materials, including detailed protocols for experimental design and troubleshooting, which enable researchers and clinicians to optimize their studies.
For researchers, clinicians, and pharmaceutical companies looking to enhance their understanding of gene function and disease mechanisms, FAM149B1 Gene Knockout Cell Lines offer a powerful solution. With our extensive experience in the development and production of biological products, we provide high-quality, validated cell lines that meet rigorous scientific standards, helping to push the boundaries of research and therapeutic discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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