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FAAP24 Knockout Cell Lines

Gene: FAAP24

Official Full Name: FA core complex associated protein 24provided by HGNC

Gene Summary: FAAP24 is a component of the Fanconi anemia (FA) core complex (see MIM 227650), which plays a crucial role in DNA damage response (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23466 FAAP24 Knockout cell line (HeLa) Human FAAP24 1:3~1:6 Negative Online Inquiry
KO23467 FAAP24 Knockout cell line (HCT 116) Human FAAP24 1:2~1:4 Negative Online Inquiry
KO23468 FAAP24 Knockout cell line (HEK293) Human FAAP24 1:3~1:6 Negative Online Inquiry
KO23469 FAAP24 Knockout cell line (A549) Human FAAP24 1:3~1:4 Negative Online Inquiry

Background

FAAP24 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed for the functional characterization of the FAAP24 gene, which is implicated in DNA damage repair. These genetically modified cell lines are created using CRISPR/Cas9 technology, allowing for precise deletions of the FAAP24 gene, thereby enabling researchers to study its role in cellular processes such as genomic stability, cell cycle regulation, and the response to genotoxic stress.

The primary function of the FAAP24 Gene Knockout Cell Lines is to provide a model system for elucidating the biological consequences of FAAP24 absence. By disrupting this gene, researchers can investigate changes in key pathways involved in DNA repair mechanisms, particularly those linked to the Fanconi anemia pathway. The resulting phenotypic changes observed in these knockout models can shed light on the contributions of FAAP24 to various cellular functions and its potential involvement in oncogenesis.

The scientific importance of these cell lines extends to both research and clinical applications. In research, they serve as valuable tools for studying the molecular underpinnings of diseases associated with defective DNA repair, including cancer, thereby advancing our understanding of tumor biology. Clinically, these cell lines can be used for drug screening and the development of therapeutic strategies targeting DNA repair deficiencies.

What sets FAAP24 Gene Knockout Cell Lines apart from alternative models is their unparalleled specificity and ease of use, providing researchers with robust and reproducible results. Designed for versatility, they are suitable for a wide range of experiments, from basic research to high-throughput screening, allowing for a multifaceted approach to studying gene function.

The value of this product to researchers and clinicians lies in its ability to facilitate groundbreaking discoveries by enabling accurate modeling of genetic conditions and disease states associated with FAAP24 dysfunction. This can lead to insights that drive innovative approaches in diagnostics and therapeutics.

Our company is dedicated to providing high-quality biological products that empower scientific research. With extensive experience in genetic engineering and a commitment to supporting the scientific community, we strive to deliver solutions that enhance research capabilities and foster significant advancements in health sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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