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EMX1 Knockout Cell Lines

Gene: EMX1

Official Full Name: empty spiracles homeobox 1provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in brain development; neuron differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; neuroepithelial cell differentiation; and regulation of oligodendrocyte progenitor proliferation. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05383 EMX1 Knockout cell line (HCT 116) Human EMX1 1:2~1:4 Negative Online Inquiry
KO05384 EMX1 Knockout cell line (HEK293) Human EMX1 1:3~1:6 Negative Online Inquiry

Background

EMX1 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of the EMX1 gene, which encodes a transcription factor integral to various developmental processes, particularly in the brain. Utilizing CRISPR/Cas9 technology, these cell lines have been genetically engineered to produce a complete knockout of the EMX1 gene, allowing researchers to explore the gene’s functional roles, its contributions to neural development, and its potential implications in neurodevelopmental disorders.

The primary function of EMX1 Gene Knockout Cell Lines lies in their ability to mimic an EMX1-deficient state, enabling in-depth investigations into gene regulation and the downstream effects on cellular pathways. By comparing these knockout cells to wild-type counterparts, researchers can delineate the specific mechanisms by which EMX1 modulates cellular behavior, assists in shaping the cortex, and influences neuronal differentiation. This cellular model is crucial for dissecting the molecular basis of pathologies related to EMX1, such as epilepsy and schizophrenia, thereby providing insights into potential therapeutic targets.

In both research laboratories and clinical settings, EMX1 Gene Knockout Cell Lines are invaluable for drug screening and biomarker discovery. Their precise genetic modification allows for controlled experiments that can yield reproducible results, making them a superior choice compared to traditional methods such as knockdown approaches or spontaneous mutation-based models. Furthermore, these cell lines can serve as effective platforms for testing potential therapies aimed at correcting deficits linked to EMX1 dysfunction.

The unique selling points of EMX1 Gene Knockout Cell Lines include their high specificity, reproducibility, and the ability to fast-track research timelines through streamlined experimental design. For researchers and clinicians aiming to illuminate the complexities of neural development or identify new avenues for intervention, these cell lines present a compelling tool that can significantly enhance their investigations.

At our company, we specialize in producing high-quality biological products, and our EMX1 Gene Knockout Cell Lines reflect our commitment to advancing scientific research by providing reliable, innovative solutions tailored to the evolving needs of the biomedical community.

Please note that all services are for research use only. Not intended for any clinical use.

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