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ELMO2 Knockout Cell Lines

Gene: ELMO2

Official Full Name: engulfment and cell motility 2provided by HGNC

Gene Summary: The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18032 ELMO2 Knockout cell line (HeLa) Human ELMO2 1:3~1:6 Negative Online Inquiry
KO18033 ELMO2 Knockout cell line (HCT 116) Human ELMO2 1:2~1:4 Negative Online Inquiry
KO18034 ELMO2 Knockout cell line (HEK293) Human ELMO2 1:3~1:6 Negative Online Inquiry
KO18035 ELMO2 Knockout cell line (A549) Human ELMO2 1:3~1:4 Negative Online Inquiry

Background

ELMO2 Gene Knockout Cell Lines are highly specialized cellular models designed to facilitate the study of the ELMO2 gene's role in various biological processes and disease pathways. ELMO2 (Engulfment and Cell Motility 2) is a gene known to influence cell migration, proliferation, and apoptosis, making it significant for understanding cancer biology and developmental processes. The knockout of this gene in these cell lines is achieved using CRISPR-Cas9 technology, which precisely edits the genome, enabling researchers to investigate the functional consequences of ELMO2 loss.

The key function of these cell lines is to serve as a powerful tool for elucidating the mechanisms by which ELMO2 contributes to cellular behavior. By comparing the knockout cells to wild-type counterparts, researchers can gain insights into the molecular pathways regulated by ELMO2 and its interactions with other proteins involved in intracellular signaling. This understanding is pivotal for identifying potential therapeutic targets in oncology and regenerative medicine.

The scientific importance of ELMO2 Gene Knockout Cell Lines extends to various applications, including drug screening, genetic studies, and the exploration of signaling pathways related to metastasis and tumor formation. In clinical settings, these cell lines can be instrumental in developing targeted therapies that may mitigate the effects of diseases linked to ELMO2 dysregulation.

What sets our ELMO2 Gene Knockout Cell Lines apart from alternative models is their robustness and reliability. Developed under stringent quality control conditions, these cell lines are validated for consistent performance, thus providing researchers with reproducible results. Additionally, the specificity of the knockout ensures that any observed phenotypic changes can be directly attributed to ELMO2 loss, minimizing confounding factors often present in other experimental models.

For researchers and clinicians alike, ELMO2 Gene Knockout Cell Lines represent a valuable asset in the quest to unravel the complexities of cellular mechanisms and disease. Our commitment to quality and innovation in biological products underlines our expertise in providing tools that advance scientific understanding and therapeutic development. By choosing our ELMO2 Gene Knockout Cell Lines, users are equipped with essential resources that empower their research and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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