Gene: DEF8
Official Full Name: differentially expressed in FDCP 8 homologprovided by HGNC
Gene Summary: Predicted to enable metal ion binding activity. Predicted to be involved in lysosome localization; positive regulation of bone resorption; and positive regulation of ruffle assembly. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18344 | DEF8 Knockout cell line (HeLa) | Human | DEF8 | 1:3~1:6 | Negative | Online Inquiry |
KO18345 | DEF8 Knockout cell line (HCT 116) | Human | DEF8 | 1:2~1:4 | Negative | Online Inquiry |
KO18346 | DEF8 Knockout cell line (HEK293) | Human | DEF8 | 1:3~1:6 | Negative | Online Inquiry |
KO18347 | DEF8 Knockout cell line (A549) | Human | DEF8 | 1:3~1:4 | Negative | Online Inquiry |
DEF8 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the specific functions of the DEF8 gene within various biological and pathological contexts. By utilizing CRISPR-Cas9 technology, these cell lines exhibit precise mutations that lead to the complete knockout of the DEF8 gene, enabling researchers to directly assess the effects of its absence on cellular processes such as proliferation, differentiation, and response to stimuli.
The primary function of DEF8 Gene Knockout Cell Lines lies in their ability to elucidate the role of DEF8 in gene expression regulation, cellular signaling pathways, and immune responses. The precise genetic manipulation allows researchers to dissect the downstream effects of DEF8's loss, providing invaluable insights into its physiological relevance and potential linkages to disease processes, particularly in cancer and autoimmune conditions.
In research and clinical settings, these cell lines serve as a crucial tool for investigating disease mechanisms and screening potential therapeutic agents. By enabling researchers to compare wild-type and knockout cell behaviors, DEF8 knockout lines facilitate a deeper understanding of gene function and pathology, paving the way for novel treatment strategies and biomarker discoveries.
Compared to other gene knockout models, the DEF8 Gene Knockout Cell Lines offer remarkable specificity and reproducibility, ensuring consistent results across experiments. Moreover, they are readily adaptable for high-throughput screening applications, making them indispensable for laboratories focused on drug discovery and cellular biology.
For researchers seeking to advance their understanding of gene function within a clinical or experimental framework, the DEF8 Gene Knockout Cell Lines represent an unparalleled resource. Our company prides itself on its expertise in producing high-quality biological products that empower cutting-edge research, providing scientists with the reliable tools necessary for groundbreaking discoveries in molecular biology and genetics.
Please note that all services are for research use only. Not intended for any clinical use.
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