Gene: CUL9
Official Full Name: cullin 9provided by HGNC
Gene Summary: Predicted to enable ubiquitin protein ligase activity. Involved in microtubule cytoskeleton organization; protein ubiquitination; and regulation of mitotic nuclear division. Located in cytosol. Part of cullin-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05880 | CUL9 Knockout cell line (HeLa) | Human | CUL9 | 1:3~1:6 | Negative | Online Inquiry |
KO05881 | CUL9 Knockout cell line (HCT 116) | Human | CUL9 | 1:2~1:4 | Negative | Online Inquiry |
KO05882 | CUL9 Knockout cell line (HEK293) | Human | CUL9 | 1:3~1:6 | Negative | Online Inquiry |
KO05883 | CUL9 Knockout cell line (A549) | Human | CUL9 | 1:3~1:4 | Negative | Online Inquiry |
CUL9 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the CUL9 gene, a crucial component of the ubiquitin-proteasome system involved in various cellular processes, including cell cycle regulation and DNA repair. These knockout cell lines serve as an invaluable tool for researchers aiming to dissect the functional role of CUL9 in pathology, particularly in cancer and neurodegenerative diseases.
The key function of CUL9 knockout cell lines lies in their ability to provide a controlled environment for evaluating the effects of CUL9 gene disruption. By comparing these knockout cells to their wild-type counterparts, researchers can elucidate the gene's role in critical signaling pathways and its involvement in ubiquitination processes. This mechanistic insight can lead to a deeper understanding of not only normal cellular functions but also the dysregulation seen in various diseases.
The scientific importance of CUL9 knockout cell lines is underscored by their capacity to contribute to novel therapeutic strategies. In clinical settings, these cell lines can be pivotal in drug screening initiatives or in optimizing combination therapies, targeting pathways influenced by CUL9. This capability positions them at the cutting edge of translational research focused on developing targeted interventions for conditions associated with aberrant CUL9 activity.
What sets our CUL9 Gene Knockout Cell Lines apart from alternatives is their high specificity and validated genetic modifications, ensuring robust and reproducible results. Unlike other models, our cell lines are meticulously characterized for optimal performance, providing researchers with a trustworthy resource that minimizes variability and accelerates discovery timelines.
The value of CUL9 Gene Knockout Cell Lines for researchers and clinicians is evident, as they enable a deeper understanding of disease mechanisms, support the development of cutting-edge therapies, and improve experimental reproducibility. Trust in our expertise stems from years of dedication to advancing biological research, underscored by a commitment to quality and innovation in the production of specialized research tools. Through our comprehensive offerings, we support scientists in pushing the boundaries of discovery and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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