Home / CSKMT Knockout Cell Lines

CSKMT Knockout Cell Lines

Gene: CSKMT

Official Full Name: citrate synthase lysine methyltransferaseprovided by HGNC

Gene Summary: Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; and peptidyl-lysine trimethylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18511 CSKMT Knockout cell line (HeLa) Human CSKMT 1:3~1:6 Negative Online Inquiry
KO18512 CSKMT Knockout cell line (HCT 116) Human CSKMT 1:2~1:4 Negative Online Inquiry
KO18513 CSKMT Knockout cell line (A549) Human CSKMT 1:3~1:4 Negative Online Inquiry

Background

CSKMT Gene Knockout Cell Lines are engineered cellular models created for the precise study of gene function and gene editing applications. These cell lines are generated through state-of-the-art CRISPR-Cas9 technology, allowing researchers to eliminate the expression of specific genes with high accuracy. This targeted knockout approach facilitates detailed investigations into gene interactions, signaling pathways, and cellular responses, making it an invaluable tool for elucidating the roles of genes in various biological processes and diseases.

The mechanism of action involves the introduction of guide RNAs that direct the Cas9 endonuclease to a specific genomic location, where it generates double-strand breaks. The subsequent repair processes can lead to insertions or deletions that disrupt the gene’s coding sequence, resulting in a complete loss of function. This knockout methodology enables researchers to dissect molecular pathways and contribute to the understanding of genetic contributions to diseases, such as cancer and metabolic disorders.

In clinical and research settings, CSKMT Gene Knockout Cell Lines are particularly significant for their role in drug discovery and testing. They can be utilized to identify potential therapeutic targets, assess drug efficacy, and investigate off-target effects, which are critical for advancing personalized medicine. Their robustness ensures reproducibility across experiments, supporting consistent and reliable data.

Compared to traditional methods of gene manipulation, CSKMT Gene Knockout Cell Lines offer several advantages. These include enhanced specificity, reduced time and effort in the genetic modification process, and the ability to create multiple knockout variants from a single cell line. Such features streamline experimental designs, allowing researchers to focus on outcomes rather than the cumbersome genetic engineering process.

For researchers and clinicians aiming to deepen their understanding of gene function or develop novel therapeutics, CSKMT Gene Knockout Cell Lines represent a powerful and essential resource. Our company excels in the manufacturing of cutting-edge biological products, providing high-quality and reliable reagents that empower scientific advancement and innovation in gene research.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.