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COPS7B Knockout Cell Lines

Gene: COPS7B

Official Full Name: COP9 signalosome subunit 7Bprovided by HGNC

Gene Summary: Involved in protein deneddylation. Located in nucleoplasm. Part of COP9 signalosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18593 COPS7B Knockout cell line (HeLa) Human COPS7B 1:3~1:6 Negative Online Inquiry
KO18594 COPS7B Knockout cell line (HCT 116) Human COPS7B 1:2~1:4 Negative Online Inquiry
KO18595 COPS7B Knockout cell line (HEK293) Human COPS7B 1:3~1:6 Negative Online Inquiry
KO18596 COPS7B Knockout cell line (A549) Human COPS7B 1:3~1:4 Negative Online Inquiry

Background

COPS7B Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the COPS7B gene, playing a pivotal role in the ubiquitin-proteasome pathway. This gene has been associated with various cellular processes, including protein degradation, signal transduction, and stress responses. By utilizing these knockout cell lines, researchers can study the downstream effects of COPS7B inhibition, including alterations in protein homeostasis and cellular responses to oxidative stress.

The key mechanism underlying the function of COPS7B is its involvement in the deubiquitination of proteins, which is essential for maintaining proper protein turnover within the cell. By knocking out this gene, scientists can gain insights into the pathophysiological consequences of diminished deubiquitination, leading to enhanced understanding of various diseases, including cancer and neurodegenerative disorders. These cell lines are invaluable tools in both basic and applied research settings, allowing for the exploration of gene function, drug responses, and cellular mechanisms in disease.

One of the advantages of COPS7B Gene Knockout Cell Lines is their specificity and precision in targeting the gene of interest, enabling researchers to achieve more reliable and reproducible results compared to traditional methods that may affect multiple pathways. This level of specificity reduces the likelihood of off-target effects and enables clearer interpretations of experimental outcomes.

Moreover, the availability of these knockout cell lines provides researchers and clinicians with a robust platform for investigating therapeutic avenues, drug development, and potential biomarkers for various diseases. This makes COPS7B Gene Knockout Cell Lines a crucial asset for laboratories focused on cutting-edge research and translational science.

With a longstanding commitment to excellence in the production of high-quality biological products, our company delivers reliable, well-characterized cell lines that empower scientists and clinicians to unlock new discoveries and advance their research initiatives effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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