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CCNDBP1 Knockout Cell Lines

Gene: CCNDBP1

Official Full Name: cyclin D1 binding protein 1provided by HGNC

Gene Summary: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29092 CCNDBP1 Knockout cell line (HeLa) Human CCNDBP1 1:3~1:6 Negative Online Inquiry
KO29093 CCNDBP1 Knockout cell line (HCT 116) Human CCNDBP1 1:2~1:4 Negative Online Inquiry
KO29094 CCNDBP1 Knockout cell line (HEK293) Human CCNDBP1 1:3~1:6 Negative Online Inquiry
KO29095 CCNDBP1 Knockout cell line (A549) Human CCNDBP1 1:3~1:4 Negative Online Inquiry

Background

CCNDBP1 Gene Knockout Cell Lines represent a pioneering resource in genetic research and cellular biology, specifically designed to facilitate the study of the CCNDBP1 gene, which encodes a protein implicated in various cellular processes, including cell proliferation, differentiation, and response to stress. These knockout cell lines have been meticulously engineered to disable the CCNDBP1 gene, allowing researchers to explore the resultant phenotypic changes and elucidate the gene's role in disease mechanisms, particularly in cancer and metabolic disorders.

The functionality of CCNDBP1 Gene Knockout Cell Lines is primarily derived from the CRISPR-Cas9 gene-editing technology used in their development. By precisely targeting and excising the CCNDBP1 gene, these cell lines provide a clean model system that eliminates confounding factors, thus enabling the study of gene function and expression pathways. Researchers can observe how the loss of CCNDBP1 affects cellular behavior, signaling pathways, and gene regulatory networks, contributing valuable insights into its biological significance.

In both research and clinical applications, these cell lines play a crucial role in drug discovery and development, allowing for the screening of potential therapeutics and understanding mechanisms of action. Furthermore, they can facilitate the identification of new biomarkers relevant to various diseases, thus bolstering their utility in personalized medicine approaches.

The CCNDBP1 Gene Knockout Cell Lines offer several advantages over similar products on the market. They provide a higher degree of specificity and reliability, due to extensive validation through functional assays, which establish their authenticity and reproducibility. Moreover, these cell lines are backed by comprehensive technical support, ensuring that users have access to the resources needed to maximize their experimental outcomes.

In summary, CCNDBP1 Gene Knockout Cell Lines are invaluable to researchers and clinicians alike, providing a critical tool for advancing our understanding of gene function and disease pathology. The depth of our company’s expertise in molecular biology coupled with a commitment to quality assurance ensures that our biological products meet the highest scientific standards, driving innovation and discovery in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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