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CCDC28B Knockout Cell Lines

Gene: CCDC28B

Official Full Name: coiled-coil domain containing 28Bprovided by HGNC

Gene Summary: The product of this gene localizes to centrosomes and basal bodies. The protein colocalizes with several proteins associated with Bardet-Biedl syndrome (BBS) and participates in the regulation of cilia development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19030 CCDC28B Knockout cell line (HeLa) Human CCDC28B 1:3~1:6 Negative Online Inquiry
KO19031 CCDC28B Knockout cell line (HCT 116) Human CCDC28B 1:2~1:4 Negative Online Inquiry
KO19032 CCDC28B Knockout cell line (HEK293) Human CCDC28B 1:3~1:6 Negative Online Inquiry
KO19033 CCDC28B Knockout cell line (A549) Human CCDC28B 1:3~1:4 Negative Online Inquiry

Background

CCDC28B Gene Knockout Cell Lines are genetically engineered cell lines that feature a targeted disruption of the CCDC28B gene, which encodes a protein involved in cellular processes such as cytokinesis and cellular organization. These knockout models serve as invaluable tools in elucidating the functional role of CCDC28B, particularly in the context of cell division and its implications in several diseases, including cancer and genetic disorders.

The key mechanism underlying the utility of CCDC28B Gene Knockout Cell Lines lies in their ability to allow researchers to observe the phenotypic changes that occur in the absence of the CCDC28B gene. By using CRISPR-Cas9 technology or other gene-editing methods, these cell lines facilitate the study of gene function through various assays, including proliferation, migration, and invasion tests. Additionally, they enable the investigation of molecular pathways in which CCDC28B is involved, expanding our understanding of cell biology and disease mechanisms.

From a scientific standpoint, CCDC28B Gene Knockout Cell Lines have significant applications in both basic research and clinical settings. They provide insights into the gene’s role in diseases linked to abnormal cell division and can aid in the identification of potential therapeutic targets. Their relevance is further highlighted in drug discovery and developmental biology, where evaluating the impact of molecular inhibitors or activators on cell behavior becomes vital.

Compared to traditional tools for gene disruption, such as RNA interference, CCDC28B Gene Knockout Cell Lines offer the advantage of stable genetic modification, ensuring consistent and reproducible results across experiments. This stability allows for a more precise exploration of long-term effects and interactions within complex biological systems.

For researchers and clinicians looking to investigate the critical roles of CCDC28B in human health and disease, our knockout cell lines serve as an essential resource. Our company specializes in advanced genetic engineering technologies and provides high-quality biological products designed to meet the evolving needs of the scientific community. By choosing our CCDC28B Gene Knockout Cell Lines, you gain access to cutting-edge tools that enhance your research capabilities and contribute to significant breakthroughs in molecular biology and medical science.

Please note that all services are for research use only. Not intended for any clinical use.

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