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C1QL3 Knockout Cell Lines

Gene: C1QL3

Official Full Name: complement C1q like 3provided by HGNC

Gene Summary: Predicted to enable identical protein binding activity. Predicted to be involved in neurotransmitter receptor localization to postsynaptic specialization membrane and postsynaptic density assembly. Predicted to act upstream of or within regulation of synapse organization. Predicted to be located in extracellular region. Predicted to be part of collagen trimer. Predicted to be active in glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and synaptic cleft. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21031 C1QL3 Knockout cell line (HCT 116) Human C1QL3 1:2~1:4 Negative Online Inquiry
KO21032 C1QL3 Knockout cell line (A549) Human C1QL3 1:3~1:4 Negative Online Inquiry

Background

C1QL3 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the C1QL3 gene's function and its associated biological pathways. By utilizing CRISPR/Cas9 gene-editing technology, these cell lines facilitate the precise disruption of the C1QL3 gene, resulting in a complete knockout that enables researchers to investigate the gene’s role in various physiological and pathological processes.

These cell lines function as versatile tools for assessing the molecular mechanisms governed by C1QL3, including its involvement in neuronal development, synaptic functions, and potential implications in neurodegenerative diseases. By providing a controlled environment free from C1QL3 expression, scientists can examine how the lack of this gene affects cellular signaling, protein interactions, and metabolic pathways. The ability to create knockouts allows for comprehensive studies on gene function, facilitating advancements in understanding genetic influences on cellular behavior and disease mechanisms.

In terms of scientific significance, C1QL3 Gene Knockout Cell Lines have broad applications in research, from basic studies in molecular biology and genetics to potential therapeutic development. They are particularly valuable in the exploration of neurobiology, offering insights that are crucial for developing targeted interventions for disorders linked to C1QL3 dysregulation.

Compared to traditional knockout methods, these cell lines provide a more efficient and reliable approach, minimizing off-target effects and enhancing specificity. The advanced editing technique ensures that researchers can achieve consistent results across experiments, making these cell lines an indispensable addition to any laboratory focused on functional genomics.

For researchers and clinicians seeking to delve into gene-function relationships, C1QL3 Gene Knockout Cell Lines offer an unparalleled opportunity for innovation and discovery. With extensive expertise in gene editing and cellular model development, our company is dedicated to supplying high-quality biological products that propel cutting-edge research and therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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