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ASB16 Knockout Cell Lines

Gene: ASB16

Official Full Name: ankyrin repeat and SOCS box containing 16provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22829 ASB16 Knockout cell line (HeLa) Human ASB16 1:3~1:6 Negative Online Inquiry
KO22830 ASB16 Knockout cell line (HCT 116) Human ASB16 1:2~1:4 Negative Online Inquiry
KO22831 ASB16 Knockout cell line (HEK293) Human ASB16 1:3~1:6 Negative Online Inquiry

Background

ASB16 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function and role of the ASB16 gene in various biological processes. These knockout models are created through advanced CRISPR/Cas9 gene-editing technology, allowing for precise disruption of the ASB16 gene, which is implicated in mechanisms related to cellular differentiation, proliferation, and signaling pathways.

The primary function of ASB16 Gene Knockout Cell Lines is to facilitate the investigation of the biological activities and potential therapeutic targets associated with ASB16. By removing the gene's expression, researchers can elucidate its role in cellular responses to external stimuli, including stress responses and metabolic processes. This can lead to insights into how alterations in ASB16 function might contribute to diseases, including certain cancers and metabolic disorders.

The scientific importance of these knockout cell lines cannot be overstated. They serve as invaluable tools in both research and clinical settings, enabling scientists to dissect gene function and interactions within complex biological networks. These cell lines are instrumental for drug discovery, testing potential therapeutics, and understanding gene-environment interactions—providing significance that could translate into novel therapeutic strategies for disease management.

Compared to alternative models, ASB16 Gene Knockout Cell Lines offer enhanced specificity and reliability. Traditional methods, such as shRNA interference or chemical inhibition, can produce off-target effects or non-specific responses, whereas CRISPR-based knockouts provide a clean deletion that allows for more accurate functional characterizations. Additionally, as a ready-to-use product, these cell lines save valuable time for researchers, allowing them to advance their studies without the need to develop a cell line from scratch.

For researchers and clinicians focused on cutting-edge genetics and cell biology, ASB16 Gene Knockout Cell Lines present a powerful solution to explore gene functionality with high fidelity. As a company deeply committed to advancing genetic research, we offer high-quality biological products that meet rigorous scientific standards, positioning our clients at the forefront of discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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