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ARHGEF17 Knockout Cell Lines

Gene: ARHGEF17

Official Full Name: Rho guanine nucleotide exchange factor 17provided by HGNC

Gene Summary: Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within actin cytoskeleton organization. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32692 ARHGEF17 Knockout cell line (HeLa) Human ARHGEF17 1:3~1:6 Negative Online Inquiry
KO32693 ARHGEF17 Knockout cell line (HCT 116) Human ARHGEF17 1:2~1:4 Negative Online Inquiry
KO32694 ARHGEF17 Knockout cell line (HEK293) Human ARHGEF17 1:3~1:6 Negative Online Inquiry
KO32695 ARHGEF17 Knockout cell line (A549) Human ARHGEF17 1:3~1:4 Negative Online Inquiry

Background

ARHGEF17 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the ARHGEF17 gene, which plays a crucial role in various cellular processes including cytoskeletal dynamics and signal transduction. These knockout models provide researchers with a unique tool to investigate the effects of the absence of this gene in cellular behavior, helping to elucidate its contributions to physiological and pathological conditions.

The key functions of ARHGEF17 involve its activity as a guanine nucleotide exchange factor (GEF) for Rho GTPases, which are pivotal in regulating membrane dynamics, cell migration, and proliferation. By utilizing ARHGEF17 Knockout Cell Lines, researchers can explore these mechanisms in detail, making it possible to examine how the loss of this gene impacts signaling pathways involved in cancer progression and other diseases.

Scientifically, these cell lines are invaluable in both research and clinical settings, facilitating high-throughput screening, drug discovery, and pathway analysis. Understanding the role of ARHGEF17 can lead to insights into therapeutic targets for diseases where Rho GTPases are implicated, enabling the development of more effective treatment strategies.

What sets ARHGEF17 Gene Knockout Cell Lines apart from alternative models is their robust validation, precise gene editing through CRISPR technology, and a complete characterization of the phenotypic changes. This ensures that researchers can confidently attribute observed effects to the knockout of ARHGEF17.

Moreover, the availability of these cell lines empowers researchers and clinicians to significantly advance their understanding of complex biological processes, paving the way for innovative therapeutic interventions. Our company prides itself on providing high-quality, precise genetic tools that facilitate discovery and drive scientific advancements. With our expertise in gene editing technologies and commitment to excellence, we ensure that our products meet the highest standards for research applicability and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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