Gene: APCDD1
Official Full Name: APC down-regulated 1provided by HGNC
Gene Summary: This locus encodes an inhibitor of the Wnt signaling pathway. Mutations at this locus have been associated with hereditary hypotrichosis simplex. Increased expression of this gene may also be associated with colorectal carcinogenesis.[provided by RefSeq, Sep 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23719 | APCDD1 Knockout cell line (HEK293) | Human | APCDD1 | 1:3~1:6 | Negative | Online Inquiry |
APCDD1 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the biological implications and regulatory mechanisms of the APCDD1 gene. This product utilizes state-of-the-art CRISPR-Cas9 technology to induce targeted mutations in the APCDD1 gene, which encodes a protein involved in the regulation of the Wnt signaling pathway, significant for cell proliferation and differentiation. By knocking out this gene, researchers can analyze the resultant phenotypic changes and delineate the role of APCDD1 in various cellular processes, thus providing insights into conditions such as cancer and developmental disorders.
The unique mechanism of these knockout cell lines allows for the interrogation of gene function through controlled experiments. With the APCDD1 gene inactivated, researchers can evaluate downstream effects on Wnt signaling activation, contributing to a more profound understanding of cancer metastasis and stem cell maintenance. This model serves as a pivotal tool for drug discovery, genetic interaction studies, and cellular response assessments, making it invaluable in both academic and industrial research contexts.
What sets these APCDD1 knockout cell lines apart from conventional models is their precision and reliability. Each cell line is rigorously validated for mutations, ensuring reproducibility in experimental outcomes, which is often a challenge in traditional gene knockout approaches.
For researchers and clinicians aiming to uncover the complexities of gene function in health and disease, the APCDD1 Gene Knockout Cell Lines offer a cutting-edge resource that facilitates groundbreaking discoveries. Our company specializes in providing high-quality cellular models backed by extensive expertise in molecular biology and genetics, ensuring that you receive products tailored to meet your research needs effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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