Gene: AKIRIN1
Official Full Name: akirin 1provided by HGNC
Gene Summary: Predicted to enable transcription coregulator activity. Predicted to be involved in several processes, including myoblast migration involved in skeletal muscle regeneration; negative regulation of satellite cell differentiation; and positive regulation of lamellipodium assembly. Located in nuclear membrane and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19915 | AKIRIN1 Knockout cell line (HeLa) | Human | AKIRIN1 | 1:3~1:6 | Negative | Online Inquiry |
KO19916 | AKIRIN1 Knockout cell line (HCT 116) | Human | AKIRIN1 | 1:2~1:4 | Negative | Online Inquiry |
KO19917 | AKIRIN1 Knockout cell line (HEK293) | Human | AKIRIN1 | 1:3~1:6 | Negative | Online Inquiry |
KO19918 | AKIRIN1 Knockout cell line (A549) | Human | AKIRIN1 | 1:3~1:4 | Negative | Online Inquiry |
AKIRIN1 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to eliminate the expression of the AKIRIN1 gene. This gene plays a significant role in the regulation of immune responses and muscle development, making it a critical target for various biological research and therapeutic applications. The cell lines are constructed using CRISPR-Cas9 technology, a precise gene-editing tool that facilitates the targeted disruption of genetic sequences, providing researchers with a reliable means to study gene function and its implications in disease.
The key function of these knockout cell lines is to serve as a platform for investigating the role of AKIRIN1 in crucial cellular processes such as inflammation, myogenesis, and stress responses. By manipulating the AKIRIN1 pathway, scientists can elucidate its involvement in conditions such as muscular dystrophies, autoimmune disorders, and other metabolic diseases. The utilization of these cell lines can foster breakthroughs in understanding disease mechanisms and the development of potential therapies.
The scientific importance of AKIRIN1 Gene Knockout Cell Lines extends to both research and clinical settings, where they can be applied in drug discovery, biomarker identification, and validation of therapeutic targets. These lines allow for reproducibility and consistency in experimental design, facilitating the generation of robust data that can lead to meaningful insights.
One of the unique selling points of our AKIRIN1 Gene Knockout Cell Lines is their high specificity and efficiency in gene knockout compared to traditional methods such as homologous recombination. Furthermore, our cell lines are validated for both genetic integrity and functional performance, providing assurances to researchers regarding the reliability of their results.
Researchers and clinicians seeking to unravel the complexities of gene function and its implications in health and disease will find tremendous value in these cell lines. They represent a powerful tool for both exploratory science and translational research, offering invaluable insights into the intricate biological networks governing various physiological conditions.
Our company is committed to advancing scientific discovery by providing high-quality, innovative biological products that empower researchers to push the boundaries of knowledge and therapeutic development. With a focus on customer support and product integrity, we strive to be a trusted partner in the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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