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ADCK5 Knockout Cell Lines

Gene: ADCK5

Official Full Name: aarF domain containing kinase 5provided by HGNC

Gene Summary: Predicted to enable protein serine/threonine kinase activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO36220 ADCK5 Knockout cell line (HeLa) Human ADCK5 1:3~1:6 Negative Online Inquiry
KO36221 ADCK5 Knockout cell line (HCT 116) Human ADCK5 1:2~1:4 Negative Online Inquiry
KO36222 ADCK5 Knockout cell line (HEK293) Human ADCK5 1:3~1:6 Negative Online Inquiry
KO36223 ADCK5 Knockout cell line (A549) Human ADCK5 1:3~1:4 Negative Online Inquiry

Background

ADCK5 Gene Knockout Cell Lines are specialized cell lines that have undergone genetic modification to inactivate the ADCK5 gene, which is implicated in mitochondrial function and energy metabolism. By systematically editing this gene, researchers can create a cellular model that mimics the pathophysiological conditions associated with ADCK5-related disorders, providing invaluable insights into disease mechanisms and potential therapeutic targets.

The ADCK5 gene encodes a protein involved in the assembly of coenzyme Q, a crucial component of the electron transport chain, which is essential for ATP production in mitochondria. The knockout of ADCK5 disrupts this pathway, leading to altered cellular respiration and energy production, making these cell lines instrumental for studying mitochondrial dysfunction and metabolic disorders.

In research and clinical applications, ADCK5 Gene Knockout Cell Lines serve as a valuable tool for investigating the role of ADCK5 in various diseases, including but not limited to, mitochondrial myopathies and neurodegenerative conditions. Researchers can study the molecular pathways that are affected by the loss of ADCK5 function, providing a platform for the discovery of potential therapeutic strategies and the development of new drugs aimed at ameliorating the symptoms associated with mitochondrial dysfunction.

What sets our ADCK5 Gene Knockout Cell Lines apart from similar products on the market is their high fidelity in gene editing, ensuring precise and reproducible results. The optimized cell culture conditions accompanying our knockout lines facilitate ease of use, making them accessible for both experienced researchers and those new to genetic studies. Furthermore, our cell lines come with extensive characterization data, allowing users to leverage a wealth of background information to inform their experiments.

Overall, the ADCK5 Gene Knockout Cell Lines represent a critical asset for researchers and clinicians focused on mitochondrial biology and related disorders. By utilizing our expertly developed cell lines, you can accelerate your research, increase the reproducibility of your results, and potentially discover new avenues for treatment. Our company prides itself on its cutting-edge technologies and commitment to supporting the scientific community through innovative biological products that empower research and advancements in health.

Please note that all services are for research use only. Not intended for any clinical use.

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