Gene: ADAMTS19
Official Full Name: ADAM metallopeptidase with thrombospondin type 1 motif 19provided by HGNC
Gene Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03539 | ADAMTS19 Knockout cell line (HEK293) | Human | ADAMTS19 | 1:3~1:6 | Negative | Online Inquiry |
ADAMTS19 Gene Knockout Cell Lines are genetically modified cell lines designed to provide researchers with a valuable tool for studying the functions of the ADAMTS19 gene. The ADAMTS19 gene encodes a member of the disintegrin and metalloproteinase with a thrombospondin type 1 motif (ADAMTS) family, which is implicated in various physiological and pathological processes, including extracellular matrix remodeling and cell signaling. By creating cell lines with a targeted knockout of the ADAMTS19 gene, researchers can directly observe the consequences of gene loss on cellular behavior, enabling a deeper understanding of its functional role.
These cell lines operate by utilizing CRISPR/Cas9 technology to introduce precise deletions within the ADAMTS19 locus. As a result, researchers can assess alterations in cellular processes such as proliferation, migration, and differentiation pathways, leading to insights into cancer development, wound healing, and tissue regeneration. The utility of these knockout cell lines extends beyond basic research, offering significant potential for translational applications in regenerative medicine and cancer therapy.
The scientific importance of ADAMTS19 Gene Knockout Cell Lines is underscored by their ability to reveal specific molecular interactions and biological mechanisms that alternative in vitro models may not fully capture. Compared to traditional knockdown approaches, our knockout cell lines provide a complete absence of the target gene, eliminating any residual activity that could confound experimental results. This specificity enhances the reliability of data generated, making it a superior option for rigorous experimental design.
For researchers and clinicians, these cell lines represent an invaluable resource in the exploration of gene function, disease mechanisms, and therapeutic targets. Their precision and applicability in diverse experimental contexts make them essential tools for advancing knowledge in cell biology and translational research.
As a company dedicated to innovation in genetic engineering, we leverage cutting-edge technologies to deliver high-quality biological products tailored for research needs. Our ADAMTS19 Gene Knockout Cell Lines exemplify our commitment to empowering the scientific community with robust tools for breakthrough discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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