Gene: ADAM9
Official Full Name: ADAM metallopeptidase domain 9provided by HGNC
Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00248 | ADAM9 Knockout cell line (HEK293) | Human | ADAM9 | 1:3~1:6 | Negative | Online Inquiry |
KO33893 | ADAM9 Knockout cell line (HeLa) | Human | ADAM9 | 1:3~1:6 | Negative | Online Inquiry |
KO33894 | ADAM9 Knockout cell line (HCT 116) | Human | ADAM9 | 1:2~1:4 | Negative | Online Inquiry |
KO33895 | ADAM9 Knockout cell line (A549) | Human | ADAM9 | 1:3~1:4 | Negative | Online Inquiry |
ADAM9 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology and genetic research. These cell lines are genetically engineered to have a complete, specific deletion of the ADAM9 gene, which encodes for a protein involved in various biological processes, including cell adhesion, migration, and proteolysis. By disabling this gene, researchers can effectively study the implications of ADAM9 loss in cellular behavior and its role in diseases, such as cancer and inflammatory disorders.
The key function of ADAM9 Gene Knockout Cell Lines is their ability to serve as a model system for investigating the downstream biological effects of ADAM9 gene deletion. By utilizing these cell lines, scientists can explore changes in signaling pathways, alterations in cell morphology, and differences in migratory patterns, all of which can provide insights into the role of ADAM9 in physiological and pathophysiological conditions. Furthermore, these knockout models facilitate the identification of potential therapeutic targets by providing a platform for drug screening and validation.
Scientifically, the availability of ADAM9 knockout models represents a valuable tool for understanding complex biological systems in both research and clinical settings. The implications of ADAM9 in various diseases make this product instrumental for researchers looking to unravel the molecular underpinnings of conditions such as metastasis and chronic inflammation. In contrast to traditional methods of gene silencing, which may yield transient and inconsistent results, our knockout cell lines provide stable and reproducible genetic modifications, enhancing the accuracy of experiments.
One of the standout advantages of ADAM9 Gene Knockout Cell Lines is their ease of use and integration into existing workflows. Unlike conventional models that might require extensive cultivation and optimization, these knockout lines can be immediately utilized, allowing researchers to accelerate their studies without extensive preparatory work. Furthermore, the robustness of these cell lines ensures high-quality data for publications and presentations, lending credibility to research outcomes.
Our company prides itself on a commitment to innovation and quality in the field of biological products. With our expertise in generating and characterizing knockout models, we are dedicated to supporting the scientific community by providing reliable tools that advance research aims. ADAM9 Gene Knockout Cell Lines stand as a testament to our mission: enabling researchers to push the boundaries of knowledge while offering cutting-edge products that deliver results.
Please note that all services are for research use only. Not intended for any clinical use.
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