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AAMDC Knockout Cell Lines

Gene: AAMDC

Official Full Name: adipogenesis associated Mth938 domain containingprovided by HGNC

Gene Summary: Predicted to be involved in positive regulation of fat cell differentiation. Predicted to act upstream of or within negative regulation of apoptotic process and positive regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27275 AAMDC Knockout cell line (HeLa) Human AAMDC 1:3~1:6 Negative Online Inquiry
KO27276 AAMDC Knockout cell line (HCT 116) Human AAMDC 1:2~1:4 Negative Online Inquiry
KO27277 AAMDC Knockout cell line (HEK293) Human AAMDC 1:3~1:6 Negative Online Inquiry
KO27278 AAMDC Knockout cell line (A549) Human AAMDC 1:3~1:4 Negative Online Inquiry

Background

AAMDC Gene Knockout Cell Lines are specially engineered cells that have undergone targeted genetic modifications to silence or disrupt the AAMDC gene. This innovative product is developed using advanced CRISPR-Cas9 technology, which ensures precise editing of the genome, allowing for clear and reproducible knockout of gene function. By eliminating the AAMDC gene expression, these cell lines serve as critical tools for studying the gene's role in cellular processes, disease mechanisms, and therapeutic responses.

The primary function of AAMDC Gene Knockout Cell Lines is to enable researchers to investigate the biological consequences of AAMDC gene deficiency in vitro. This allows for a detailed exploration of various cellular pathways, including those involved in differentiation, apoptosis, and immune response. The precise knockout of AAMDC facilitates functional assays and phenotypic characterization, which are essential for elucidating its involvement in pathological conditions such as cancer or metabolic disorders.

In scientific and clinical settings, these cell lines hold significant importance as they provide a reliable model for drug discovery, target validation, and therapeutic development. Their utility spans across multiple fields, including oncology, immunology, and regenerative medicine, making them versatile tools for advancing biomedical research.

One of the outstanding advantages of our AAMDC Gene Knockout Cell Lines is their superior specificity and reliability compared to traditional knockout models, which often present off-target effects and variability. The CRISPR-Cas9 system used in their creation ensures consistent results and reproducibility across experiments, thereby increasing the reliability of research outcomes.

For researchers and clinicians, the value of AAMDC Gene Knockout Cell Lines lies in their ability to facilitate mechanistic studies with a high degree of accuracy, aiding in the rapid progression from hypothesis to application. These cell lines provide an invaluable resource for understanding gene function and developing targeted therapies.

With our dedicated focus on genetic engineering and a commitment to high-quality products, we pride ourselves on delivering exceptional biological tools like the AAMDC Gene Knockout Cell Lines, positioning us at the forefront of scientific advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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