RUNX1T1 Knockout cell line (BEAS-2B)

Name: RUNX1T1 Knockout cell line (BEAS-2B)
Brand: CD Biosynsis
SKU: KOA32174
Availability: InStock

Catalog Number: KOA32174

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Specifications

Product Information
Product Name	RUNX1T1 Knockout cell line (BEAS-2B)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:3~1:4
species	Human
Gene	RUNX1T1
Gene ID	862
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM+10% FBS
Parental Cell Line	BEAS-2B
Quality Control	Genotype: RUNX1T1 Knockout cell line (BEAS-2B)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	RUNX1 partner transcriptional co-repressor 1provided by HGNC
Also known as	CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8
Gene Description	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Expression	Ubiquitous expression in endometrium (RPKM 1.9), brain (RPKM 1.3) and 22 other tissues See more

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