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RCAN1 Knockout cell line (HCT 116)

Catalog Number: KO38163

Price: Online Inquiry

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Specifications

Product Information
Product Name RCAN1 Knockout cell line (HCT 116)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:2~1:4
species Human
Gene RCAN1
Gene ID 1827
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%McCOYs 5A+10% FBS
Parental Cell Line HCT 116
Quality Control Genotype: RCAN1 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name regulator of calcineurin 1provided by HGNC
Also known as CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
Gene Description The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Expression Broad expression in liver (RPKM 56.9), placenta (RPKM 30.5) and 22 other tissues See more

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