IGFBP3 Knockout cell line (TPC-1)

Catalog Number: KOA61552

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Specifications

Product Information
Product Name	IGFBP3 Knockout cell line (TPC-1)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Epithelial-like, adherent
Passage ratio	1:5-1:8
species	Human
Gene	IGFBP3
Gene ID	3486
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90%DMEM+10%FBS
Parental Cell Line	TPC-1
Quality Control	Genotype: IGFBP3 Knockout cell line (TPC-1)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	insulin like growth factor binding protein 3provided by HGNC
Also known as	IBP3; BP-53; IBP-3; IGFBP-3
Gene Description	This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Expression	Biased expression in placenta (RPKM 686.3), endometrium (RPKM 259.6) and 7 other tissues See more

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