HSPB1 Knockout cell line (A549)

Catalog Number: KO10750

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Specifications

Product Information
Product Name	HSPB1 Knockout cell line (A549)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:3~1:4
species	Human
Gene	HSPB1
Gene ID	3315
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90% F12K+10% FBS
Parental Cell Line	A549
Quality Control	Genotype: HSPB1 Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	heat shock protein family B (small) member 1provided by HGNC
Also known as	CMT2F; HMN2B; HMND3; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102
Gene Description	This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
Expression	Broad expression in esophagus (RPKM 497.4), skin (RPKM 350.7) and 23 other tissues See more

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