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ERBIN Knockout cell line (NCM460)

Catalog Number: KOA70137

Price: Online Inquiry

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Specifications

Product Information
Product Name ERBIN Knockout cell line (NCM460)
specification 1*10^6
Storage and transportation Shipped on dry ice; Store in liquid nitrogen
Cell morphology Epithelial-like, adheren
Passage ratio 1:2~1:3
species Human
Gene ERBIN
Gene ID 55914
Build method Electroporation/Lentivirus
Mycoplasma testing negative
Cultivation system 90%RPMI-1640+10%FBS
Parental Cell Line NCM460
Quality Control Genotype: ERBIN Knockout cell line (NCM460)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name erbb2 interacting proteinprovided by HGNC
Also known as LAP2; ERBB2IP; HEL-S-78
Gene Description This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Expression Ubiquitous expression in small intestine (RPKM 17.6), lymph node (RPKM 17.5) and 25 other tissues See more

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