E. coli Metabolic Engineering Services

Design is proposed by our team and reviewed with yours before construction starts. Each intended genetic change is described in the design proposal together with its rationale, so design choices stay visible and any change to the plan is agreed rather than assumed.

Knockout-based edits are our primary modality and the default starting point for most strain programs. Knock-in and other precise edits can be evaluated case by case during design review, and the modality used for your project is written into the agreed scope.

Handoff is defined in the project scope and typically includes engineered strain stocks, construct and sequence documentation, screening and confirmation datasets, analytics results for the agreed readouts, and a final report. Items not in scope are confirmed with you before they are added.

Yes. Host and strain background are confirmed at scoping, and an existing strain can be reviewed as the starting point where it suits the target route. Where the current background limits the design space, we will discuss alternatives with you before the plan is fixed.

Named scientific contact at project start; milestone review calls.

Small-scale evaluation is the standard format offered within an engineering program, and larger-scale work is scoped separately when your project requires it. The evaluation format, readouts and sample handling are agreed with you at scoping rather than assumed.