CD33 Knockout cell line (HCT 116)

Catalog Number: KO10012

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Specifications

Product Information
Product Name	CD33 Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	CD33
Gene ID	945
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: CD33 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	CD33 moleculeprovided by HGNC
Also known as	p67; SIGLEC3; SIGLEC-3; CD33rSiglec
Gene Description	Enables protein phosphatase binding activity; protein tyrosine phosphatase activator activity; and sialic acid binding activity. Involved in several processes, including immune response-regulating signaling pathway; negative regulation of cytokine production; and negative regulation of monocyte activation. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome. [provided by Alliance of Genome Resources, Apr 2025]
Expression	Broad expression in spleen (RPKM 7.5), bone marrow (RPKM 6.6) and 19 other tissues See more

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