CD Monoamine Oxidase Inhibitor Screening Kit

Catalog Number: AKBA264

Size: 100 tests

(AKBA264)CD Monoamine Oxidase Inhibitor Screening Kit

Product Information
Product Name	CD Monoamine Oxidase Inhibitor Screening Kit
Applications	For evaluation and high-throughput screen (HTS) of monoamine oxidase modulators.
Features	Homogeneous and convenient. “Mix-incubate-measure” type assay. No wash and reagent transfer steps are involved. Robust and amenable to HTS: can be readily automated on HTS liquid handling systems for processing thousands of samples per day.
Detection Method	FL530/585nm
Sample Type	Compounds that affect monoamine oxidase (MAO) activity
Species	All
Assay Time	35 min
Expiration Date	6 months
Description	MONOAMINE OXIDASES (MAO, EC 1.4.3.4) are a family of mitochondrial enzymes that catalyze the oxidative deamination of monoamines. Two isoforms of MAO exist, MAO-A and MAO-B, with different inhibitor selectivity and tissue distribution. MAO dysfunction is thought to be responsible for a number of neurological disorders. Unusually high or low levels of MAOs in the body have been associated with depression, schizophrenia, substance abuse, attention deficit disorder, migraines, and irregular sexual maturation. MAO inhibitors are one of the major classes of drugs prescribed for the treatment of depression, Parkinson’s, and Alzheimer’s diseases. BioAssay Systems MAO Inhibitor Screening Assay Kit provides a convenient fluorimetric means to screen for MAO enzyme inhibitors. In the assay, MAO reacts with p-tyramine, a substrate for both MAO-A and MAO-B, resulting in the formation of H2O2, which is determined by a fluorimetric method (λem/ex = 585/530 nm). The assay is simple, sensitive, stable, and high-throughput adaptable.
Shipping Conditions	Shipping: On Ice
Storage	Storage: -20°C upon receipt

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CD Monoamine Oxidase Inhibitor Screening Kit