CD Farnesyltransferase Activity Assay Kit

Catalog Number: AKBA212

Size: 400 tests in 384well plate

(AKBA212)CD Farnesyltransferase Activity Assay Kit

Product Information
Product Name	CD Farnesyltransferase Activity Assay Kit
Applications	For quantitative determination of FTase enzyme activity in biological samples.
Features	Safe and convenient. Non-radioactive assay. “Mix-incubate-measure” type assay. No wash and reagent transfer steps are involved. Sensitive and accurate. Linear detection range 0.024 – 3.2 U/L FTase in a 384-well plate assay. High-throughput. Can be readily automated to assay thousands of samples per day.
Detection Method	FL340/550 nm
Sample Type	Biological Samples, Purified Enzyme
Species	All
Assay Time	60 min
Limit of Detection	0.024 U/L
Expiration Date	6 months
Description	FARNESYLTRANSFERASE (FTase, EC 2.5.1.58) catalyzes the transfer of a farnesyl group from farnesyl pyrophosphate to the cysteine residue of the C-terminus of target proteins. When not properly regulated, farnesylated proteins, including the Ras superfamily of small GTPases, can lead to developmental disorders and cancer. Simple, direct and high-throughput activity assays find wide applications for cancer research, while BioAssay Systems’ EFTS-400 assay kit provides a convenient fluorimetric method for assaying FTase activity. In this assay, FTase reacts with farnesyl pyrophosphate and the dansyl-peptide substrate releasing a product that is measurable by fluorescence (λem/ex = 340/550 nm).
Shipping Conditions	Shipping: Ice
Storage	Storage: -20°C upon receipt.

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CD Farnesyltransferase Activity Assay Kit