AKR1C1 Knockout cell line (AC16)

Catalog Number: KOA16255

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Specifications

Product Information
Product Name	AKR1C1 Knockout cell line (AC16)
specification	1*10^6
Storage and transportation	Shipped on dry ice; Store in liquid nitrogen
Cell morphology	Fibroblast-like, adherent
Passage ratio	1：3-1：4
species	Human
Gene	AKR1C1
Gene ID	1645
Build method	Electroporation/Lentivirus
Mycoplasma testing	negative
Cultivation system	90% DMEM/F12+10% FBS
Parental Cell Line	AC16
Quality Control	Genotype: AKR1C1 Knockout cell line (AC16)>95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	aldo-keto reductase family 1 member C1provided by HGNC
Also known as	C9; DD1; DDH; DDH1; H-37; HBAB; MBAB; HAKRC; DD1/DD2; 2-ALPHA-HSD; 20-ALPHA-HSD
Gene Description	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Expression	Biased expression in liver (RPKM 85.2), fat (RPKM 74.3) and 13 other tissues See more

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