Gene: ZNF43
Official Full Name: zinc finger protein 43provided by HGNC
Gene Summary: This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12349 | ZNF43 Knockout cell line (HEK293) | Human | ZNF43 | 1:3~1:6 | Negative | Online Inquiry |
KO12350 | ZNF43 Knockout cell line (A549) | Human | ZNF43 | 1:3~1:4 | Negative | Online Inquiry |
ZNF43 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the in-depth study of the ZNF43 gene's functions and its role in various biological processes. The ZNF43 gene encodes a member of the zinc finger protein family, which is critical in transcriptional regulation, influencing cellular behavior and response to environmental stimuli. By employing CRISPR-Cas9 technology, our knockout cell lines effectively disrupt the ZNF43 gene, allowing researchers to investigate the consequences of its loss-of-function in a controlled environment.
The key function of these knockout cell lines lies in their ability to shed light on ZNF43's involvement in gene expression regulation, cell differentiation, apoptosis, and neoplastic transformation. Researchers can utilize these models to evaluate downstream signaling pathways, assess alterations in cellular morphology, and identify potential compensatory mechanisms. Furthermore, these cell lines serve as vital tools in drug discovery and therapeutic intervention studies by elucidating the biological pathways that can be targeted for clinical applications.
Our ZNF43 Gene Knockout Cell Lines stand out in the biological product market due to their high specificity, reproducibility, and the comprehensive documentation provided, which includes extensive characterization data. Unlike alternative models that may yield inconsistent results owing to genetic variability, our knockout lines ensure uniformity across experiments, making them a reliable choice for both basic research and clinical investigations.
The implications of utilizing ZNF43 knockout cell lines are profound, enabling researchers to unravel critical aspects of gene regulation and its impact on health and disease mechanisms. In clinical settings, these models can contribute to the identification of novel biomarkers for diagnostic applications and potential targets for gene therapy.
With years of expertise in genomic technologies and a commitment to advancing research, our company provides high-quality cellular models that empower scientists and clinicians to achieve their research objectives efficiently and effectively. Through our innovative product offerings, we continue to support the scientific community in overcoming challenges and advancing knowledge in genetics and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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