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ZNF354B Knockout Cell Lines

Gene: ZNF354B

Official Full Name: zinc finger protein 354Bprovided by HGNC

Gene Summary: Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription corepressor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30428 ZNF354B Knockout cell line (HeLa) Human ZNF354B 1:3~1:6 Negative Online Inquiry
KO30429 ZNF354B Knockout cell line (HCT 116) Human ZNF354B 1:2~1:4 Negative Online Inquiry
KO30430 ZNF354B Knockout cell line (HEK293) Human ZNF354B 1:3~1:6 Negative Online Inquiry
KO30431 ZNF354B Knockout cell line (A549) Human ZNF354B 1:3~1:4 Negative Online Inquiry

Background

ZNF354B Gene Knockout Cell Lines represent a revolutionary tool in molecular biology, engineered specifically for in-depth exploration of the ZNF354B gene's function. ZNF354B, a member of the zinc finger protein family, is involved in crucial cellular processes such as gene regulation, apoptosis, and cell differentiation. By leveraging CRISPR-Cas9 technology, these knockout cell lines provide a robust platform for studying the gene's effects on various biological pathways, offering an unprecedented capability to elucidate its roles in health and disease.

The principal function of these cell lines lies in their ability to facilitate targeted gene disruption, allowing researchers to assess phenotypic changes resulting from the absence of ZNF354B. This mechanistic insight is essential for understanding the gene's contribution to oncogenesis, metabolic disorders, and other pathological conditions. By enabling precise genomic edits, the ZNF354B Gene Knockout Cell Lines serve as a critical resource for drug discovery and therapeutic development, supporting the identification of novel biomarkers and potential treatment targets.

In comparison to traditional gene knockdown methods such as RNA interference, our knockout cell lines provide a more permanent and specific means of gene manipulation, thus yielding more reliable and reproducible results. The minimal off-target effects associated with CRISPR technology enhance the overall validity of experimental findings, making these cell lines an invaluable asset for both academic research and clinical applications.

For researchers and clinicians keen on advancing their understanding of ZNF354B, our knockout cell lines offer a unique opportunity to explore its biological significance with a high degree of precision. This product stands out for its accessibility and ease of use, along with comprehensive technical support aimed at facilitating successful experimental outcomes.

At [Your Company Name], our team of experts specializes in providing high-quality biological products tailored to meet the evolving needs of the research community. We are committed to empowering scientists with innovative tools that pave the way for groundbreaking discoveries in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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