Gene: ZNF311
Official Full Name: zinc finger protein 311provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12313 | ZNF311 Knockout cell line (HeLa) | Human | ZNF311 | 1:3~1:6 | Negative | Online Inquiry |
ZNF311 Gene Knockout Cell Lines are engineered cellular systems specifically designed to facilitate the study of the ZNF311 gene, which plays a critical role in transcriptional regulation and various biological processes, including cell differentiation and proliferation. By completely knocking out the expression of ZNF311, these cell lines offer a unique opportunity for researchers to explore the gene's functional implications in both normal and pathological states.
The primary function of ZNF311 Gene Knockout Cell Lines is to provide a controlled platform where the absence of ZNF311 can be studied without interference from the gene's normal expression. This allows researchers to elucidate the precise biological pathways in which ZNF311 is involved by observing the resultant phenotypic and genotypic changes. Mechanistically, the cell lines allow for the dissection of gene regulatory networks, enabling a deeper understanding of how ZNF311 interacts with other transcription factors and influence cellular responses.
The scientific importance of these knockout cell lines is underscored by their broad applications in both basic research and clinical settings, particularly in cancer biology, stem cell research, and developmental biology studies. Researchers can utilize these cell lines to investigate the role of ZNF311 in tumorigenesis, cell survival mechanisms, and the modulation of gene expression during differentiation.
One of the significant advantages of ZNF311 Gene Knockout Cell Lines is their capability to serve as reliable controls in experiments, ensuring that observed effects can be attributed specifically to the absent ZNF311 gene. Compared to traditional knockdown methodologies, which may leave residual expression or affect other genes, these knockout cell lines offer a cleaner and more effective approach for functional studies.
For researchers, clinicians, and institutions focused on genetic and molecular biology, the ZNF311 Gene Knockout Cell Lines represent a valuable resource that can enhance understanding of gene function and disease mechanisms. Their unique properties are essential tools for the advancement of therapeutic strategies targeting ZNF311-related pathways.
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